rs9954153
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (G;G) | 2 | ~5x higher risk for Fuchs' dystrophy, a corneal disorder |
| (G;T) | 2 | ~2.5x higher risk for Fuchs' dystrophy, a corneal disorder |
| (T;T) | 0 | common |
| Reference | GRCh38 38.1/141 |
| Chromosome | 18 |
| Position | 55871026 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs9954153 |
| dbSNP (classic) | rs9954153 |
| ClinGen | rs9954153 |
| ebi | rs9954153 |
| HLI | rs9954153 |
| Exac | rs9954153 |
| Gnomad | rs9954153 |
| Varsome | rs9954153 |
| LitVar | rs9954153 |
| Map | rs9954153 |
| PheGenI | rs9954153 |
| Biobank | rs9954153 |
| 1000 genomes | rs9954153 |
| hgdp | rs9954153 |
| ensembl | rs9954153 |
| geneview | rs9954153 |
| scholar | rs9954153 |
| rs9954153 | |
| pharmgkb | rs9954153 |
| gwascentral | rs9954153 |
| openSNP | rs9954153 |
| 23andMe | rs9954153 |
| SNPshot | rs9954153 |
| SNPdbe | rs9954153 |
| MSV3d | rs9954153 |
| GWAS Ctlg | rs9954153 |
| GMAF | 0.1088 |
| Max Magnitude | 2 |
rs9954153 is a SNP in the transcription factor 4 TCF4 gene. It is one of several TCF4 SNPs reported to be independently associated with Fuchs' dystrophy.
| ? | (G;G) (G;T) (T;T) | 28 |
|---|---|---|
|
| ||
[PMID 22234156
] Association of TCF4 and CLU polymorphisms with Fuchs' endothelial dystrophy and implication of CLU and TGFBI proteins in the disease process
