Talk:Rs10521339
From SNPedia
According to http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1226186/table/TB3/ of those affected, 95.4% are A and 4.6% are T. Of those who are not affected, 67.7% are A and 32.3% are T.
- My guess is this research is only useful if you are CEU. Otherwise, you'd have to explain why so many Asians are baldheaded.
John Lloyd Scharf 21:58, 5 September 2011 (UTC)
- I think you've caught a mistake in the original paper. Notably the SNPs just below this one rs2223841, has very similar frequency due to linkage disequillibrium. Its frequency matches what we would expect based on the HapMap data. While this doesn't have a minus orientation, it is still and ambiguous flip. If you swap the A and T frequencies they become quite plausible. --- cariaso 22:34, 5 September 2011 (UTC)
Obviously, we cannot assume they made a mistake. Baldness is not a predominant trait and they have a small sample. John Lloyd Scharf
- Assuming they are error free would be a bigger mistake, but assuming for either side is lazy. We can check and ask. Baldness is a predominant trait [PMID 16382660]
