WT1
From SNPedia
| is a | gene |
| is | mentioned by |
| Full name | Wilms tumor 1 |
| EntrezGene | 7490 |
| PheGenI | 7490 |
| VariationViewer | 7490 |
| ClinVar | WT1 |
| GeneCards | WT1 |
| dbSNP | 7490 |
| Diseases | WT1 |
| SADR | 7490 |
| HugeNav | 7490 |
| wikipedia | WT1 |
| WT1 | |
| gopubmed | WT1 |
| EVS | WT1 |
| HEFalMp | WT1 |
| MyGene2 | WT1 |
| 23andMe | WT1 |
| UniProt | P19544 |
| Ensembl | ENSG00000184937 |
| OMIM | 607102 |
| # SNPs | 37 |
| Max Magnitude | Chromosome position | Summary | |
|---|---|---|---|
| rs1057519745 | 0 | 32,396,363 | |
| rs1060501253 | 7.5 | 32,428,031 | |
| rs121907900 | 7.5 | 32,392,020 | |
| rs121907901 | 0 | 32,392,704 | |
| rs121907902 | 0 | 32,392,013 | |
| rs121907903 | 0 | 32,392,019 | |
| rs121907904 | 0 | 32,396,313 | |
| rs121907905 | 0 | 32,392,723 | |
| rs121907906 | 7.5 | 32,392,717 | |
| rs121907907 | 0 | 32,392,682 | |
| rs121907908 | 7.5 | 32,400,025 | |
| rs121907909 | 7.5 | 32,392,032 | |
| rs121907910 | 0 | 32,392,705 | |
| rs121907911 | 7.5 | 32,434,815 | |
| rs16754 | 0 | 32,396,399 | |
| rs1799925 | 0 | 32,435,016 | |
| rs1799937 | 0 | 32,389,228 | |
| rs2234581 | 0 | 32,435,180 | |
| rs2234582 | 0 | 32,435,148 | |
| rs2234583 | 0 | 32,434,752 | |
| rs2234593 | 0 | 32,392,787 | |
| rs28941777 | 0 | 32,392,053 | |
| rs28941778 | 9 | 32,392,014 | |
| rs28941779 | 9 | 32,392,026 | |
| rs28942089 | 9 | 32,392,672 | |
| rs3930513 | 0 | 32,433,981 | |
| rs5030141 | 0 | 32,434,307 | |
| rs5030315 | 0 | 32,388,970 | |
| rs5030317 | 0 | 32,388,791 | |
| rs5030320 | 0 | 32,388,456 | |
| rs587776573 | 7.5 | 32,417,633 | |
| rs587776574 | 7.5 | 32,399,967 | |
| rs587776575 | 0 | 32,391,966 | |
| rs587776576 | 7.5 | 32,391,967 | |
| rs587776577 | 0 | 32,391,968 | |
| rs776155094 | 0 | 32,435,210 | |
| rs869025561 | 0 | 32,392,755 |
The WT1 gene located on chromosome 11 encodes the Wilms tumor protein.Wikipedia
Several dominantly inherited syndromes are associated with de novo germline mutations in and/or deletions of the WT1 gene, including GHR:
- Denys-Drash syndrome
- Frasier syndrome
- Congenital nephrotic syndrome
- Cytogenetically normal acute myeloid leukemia
- Prostate cancer
- WAGR syndrome
- Kidney cancer (Wilms tumor)
A ClinGen Actionability summary is available here and is associated with certain WT1 genotypes.
