rs3737559

minus

Geno	Mag	Summary
(C;C)	0
(G;G)	0	common in complete genomics

Make rs3737559(A;A)

Make rs3737559(A;G)

Reference

GRCh38 38.1/141

Chromosome

17

Position

43082287

Gene

BRCA1

is a	snp
is	mentioned by
dbSNP	rs3737559
dbSNP (classic)	rs3737559
ClinGen	rs3737559
ebi	rs3737559
HLI	rs3737559
Exac	rs3737559
Gnomad	rs3737559
Varsome	rs3737559
LitVar	rs3737559
Map	rs3737559
PheGenI	rs3737559
Biobank	rs3737559
1000 genomes	rs3737559
hgdp	rs3737559
ensembl	rs3737559
geneview	rs3737559
scholar	rs3737559
google	rs3737559
pharmgkb	rs3737559
gwascentral	rs3737559
openSNP	rs3737559
23andMe	rs3737559
SNPshot	rs3737559
SNPdbe	rs3737559
MSV3d	rs3737559
GWAS Ctlg	rs3737559

GMAF

0.06336

Max Magnitude

0

?

(A;A) (A;G) (G;G)

28

[PMID 21598251] Genetic polymorphisms in AURKA and BRCA1 are associated with breast cancer susceptibility in a Chinese Han population

[PMID 15743496 ] Haplotype analysis of common variants in the BRCA1 gene and risk of sporadic breast cancer.

[PMID 17428325 ] Common variants in the ATM, BRCA1, BRCA2, CHEK2 and TP53 cancer susceptibility genes are unlikely to increase breast cancer risk.

[PMID 18701471 ] Chromosome 17q12 variants contribute to risk of early-onset prostate cancer.

[PMID 19276285 ] Associations between single nucleotide polymorphisms in double-stranded DNA repair pathway genes and familial breast cancer.

[PMID 20039378 ] Estimation of genotype relative risks from pedigree data by retrospective likelihoods.

ClinVar
Risk	rs3737559(A;A)
Alt	rs3737559(A;A)
Reference	Rs3737559(G;G)
Significance	Non-pathogenic
Disease	Breast-ovarian cancer
Variation	info
Gene	BRCA1
CLNDBN	Breast-ovarian cancer, familial 1
Reversed	1
HGVS	NC_000017.10:g.41234304C>T
CLNSRC	Breast Cancer Information Core (BRCA1)
CLNACC	RCV000112322.2,

[PMID 25463638] Association of genetic polymorphisms in AURKA, BRCA1, CCNE1 and CDK2 with the risk of endometrial carcinoma and clinicopathological parameters among Chinese Han women