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Abiraterone acetate

From SNPedia

Abiraterone acetate (INN, USAN, BAN, JAN) (brand names Zytiga, Abiratas, Abretone, Abirapro) is a steroidal CYP17A1 inhibitor and by extension androgen synthesis inhibitor which is used in combination with prednisone in metastatic castration-resistant prostate cancer (mCRPC; previously called hormone-resistant or hormone-refractory prostate cancer) – i.e., prostate cancer not responding to androgen deprivation or treatment with androgen receptor antagonists.Wikipedia]

A SNP in the CYP17A1 gene, rs2486758, has been reported (in a small study) to potentially indicate mCRPC patients responding better to AA/P therapy.