GPX4
From SNPedia
is a | gene |
is | mentioned by |
EntrezGene | 2879 |
PheGenI | 2879 |
VariationViewer | 2879 |
ClinVar | GPX4 |
GeneCards | GPX4 |
dbSNP | 2879 |
Diseases | GPX4 |
SADR | 2879 |
HugeNav | 2879 |
wikipedia | GPX4 |
GPX4 | |
gopubmed | GPX4 |
EVS | GPX4 |
HEFalMp | GPX4 |
MyGene2 | GPX4 |
23andMe | GPX4 |
# SNPs | 7 |
Max Magnitude | Chromosome position | Summary | |
---|---|---|---|
rs2074451 | 0 | 1,107,036 | |
rs4807542 | 0 | 1,104,079 | |
rs713041 | 0 | 1,106,616 | |
rs757228 | 0 | 1,101,993 | |
rs757229 | 0 | 1,102,115 | |
rs769967246 | 0 | 1,105,456 | |
rs775146234 | 0 | 1,105,814 |
The GPX4 C718T SNP, rs713041, influences the concentration of lymphocyte GPx4 and other selenoproteins in vivo. The latter is consistent with competition for selenium in selenoprotein synthesis, and, at low selenium intake, the SNP thus may influence susceptibility to disease