Metoprolol
From SNPedia
Metoprolol is the generic name of a drug in the beta blocker class, typically used in the treatment of high blood pressure. Trade names for metoprolol include Lopressor, Toprol-XL, Seleken, Minax, Metrol, Betaloc, Neobloc, Corvitol.
SNPs in the ADRB1 gene may influence how well metoprolol will help lower a patient's high blood pressure; for examples, see rs1801252 and rs1801253.
[PMID 18784654] CYP2D6*4 homozygotes taking a beta blocker like metoprolol are at 4x increased risk for bradycardia; see rs3892097 for more details
See also: genoset gs185 for a related blood pressure effect connected to this drug.
