rs10116277
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (G;T) |
| Make rs10116277(G;G) |
| Make rs10116277(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 9 |
| Position | 22081398 |
| Gene | CDKN2B-AS1 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs10116277 |
| dbSNP (classic) | rs10116277 |
| ClinGen | rs10116277 |
| ebi | rs10116277 |
| HLI | rs10116277 |
| Exac | rs10116277 |
| Gnomad | rs10116277 |
| Varsome | rs10116277 |
| LitVar | rs10116277 |
| Map | rs10116277 |
| PheGenI | rs10116277 |
| Biobank | rs10116277 |
| 1000 genomes | rs10116277 |
| hgdp | rs10116277 |
| ensembl | rs10116277 |
| geneview | rs10116277 |
| scholar | rs10116277 |
| rs10116277 | |
| pharmgkb | rs10116277 |
| gwascentral | rs10116277 |
| openSNP | rs10116277 |
| 23andMe | rs10116277 |
| SNPshot | rs10116277 |
| SNPdbe | rs10116277 |
| MSV3d | rs10116277 |
| GWAS Ctlg | rs10116277 |
| GMAF | 0.3466 |
| Max Magnitude | 0 |
| ? | (G;G) (G;T) (T;T) | 28 |
|---|---|---|
|
| ||
discussed in this blog postA region of chromosome 9p21 has revealed numerous SNPs correlated with risk of myocardial infarction in a study of 2,000+ patients. This SNP, rs10116277, is highly correlated (r2=0.9) with rs2383207, as well as rs1333040 (r2=0.67). Ultimately, though, the SNP in this study (and region) with the highest disease correlation is rs10757278.
According to a DeCode report, the G allele of his SNP is associated with lower risk of abdominal aortic aneurysm (AAA). [PMID 18176561]
[PMID 21375403
] The Relationship Between Polymorphisms on Chromosome 9p21 and Age of Onset of Coronary Heart Disease in Black and White Women
[PMID 18362232] Repeated replication and a prospective meta-analysis of the association between chromosome 9p21.3 and coronary artery disease.
[PMID 18620593] Investigation of 89 candidate gene variants for effects on all-cause mortality following acute coronary syndrome.
[PMID 18704761] Molecular genetics of myocardial infarction.
[PMID 18987759] Genetic testing for atherosclerosis risk: inevitability or pipe dream?
[PMID 19463184] Worldwide patterns of haplotype diversity at 9p21.3, a locus associated with type 2 diabetes and coronary heart disease.
[PMID 19819472] Common genetic variants on chromosome 9p21 predict perioperative myocardial injury after coronary artery bypass graft surgery.
[PMID 19888323] Relationship between CAD risk genotype in the chromosome 9p21 locus and gene expression. Identification of eight new ANRIL splice variants.
[PMID 20386740] Chromosome 9p21 SNPs Associated with Multiple Disease Phenotypes Correlate with ANRIL Expression.
[PMID 20718794] Association of polymorphisms in 9p21 region with CAD in North Indian population: replication of SNPs identified through GWAS.
