rs10127939

minus

Geno	Mag	Summary
(A;A)	1	immunodeficiency, but not for 23andMe users
(T;T)	0	common in clinvar

Make rs10127939(A;T)

Reference

GRCh38 38.1/142

Chromosome

1

Position

161548543

Gene

FCGR3A

is a	snp
is	mentioned by
dbSNP	rs10127939
dbSNP (classic)	rs10127939
ClinGen	rs10127939
ebi	rs10127939
HLI	rs10127939
Exac	rs10127939
Gnomad	rs10127939
Varsome	rs10127939
LitVar	rs10127939
Map	rs10127939
PheGenI	rs10127939
Biobank	rs10127939
1000 genomes	rs10127939
hgdp	rs10127939
ensembl	rs10127939
geneview	rs10127939
scholar	rs10127939
google	rs10127939
pharmgkb	rs10127939
gwascentral	rs10127939
openSNP	rs10127939
23andMe	rs10127939
SNPshot	rs10127939
SNPdbe	rs10127939
MSV3d	rs10127939
GWAS Ctlg	rs10127939

GMAF

0.03581

Max Magnitude

1

OMIM	146740
Desc
Variant	0002
Related	also

?

(A;A) (A;C) (C;C)

ClinVar
Risk	Rs10127939(A;A) rs10127939(G;G)
Alt	Rs10127939(A;A) rs10127939(G;G)
Reference	Rs10127939(T;T)
Significance	Pathogenic
Disease	not specified Immunodeficiency 20
Variation	info
Gene	FCGR3A
CLNDBN	not specified Immunodeficiency 20
Reversed	1
HGVS	NC_000001.10:g.161518333A>C; NC_000001.10:g.161518333A>T
CLNSRC	OMIM Allelic Variant UniProtKB (protein)
CLNACC	RCV000454434.1, RCV000015953.3, RCV000454581.1,

[PMID 24375423] FcγRIIIa SNPs and haplotypes affect human IgG binding and association with lupus nephritis in African Americans

[PMID 24782186 ] Fcγ Receptor IIIa Single-Nucleotide Polymorphisms and Haplotypes Affect Human IgG Binding and Are Associated With Lupus Nephritis in African Americans