||carrier of a silent polymorphism in CYP3A5
||CYP3A5*6 homozygote; nonexpressor for CYP3A5
rs10264272, also known as 14690G>A, is a SNP in the CYP3A5 gene.
[PMID 21806386] indicates that this corresponds with CYP3A5*6, however, this seems doubtful. CYP3A5 allele nomenclature found at http://www.cypalleles.ki.se/cyp3a5.htm indicates that CYP3A5*6 (also known as 14690G>A) is a splicing defect resulting in essentially no activity in the gene. This does not correspond with dbSNP, which indicates that is a nucleotide substition (624G-A) which only results in a "silent" substitution of AAG (Lysine) to AAA (Lysine).
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