rs1026732
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | 2 | <0.70x risk for restless legs |
| (A;G) | 1.5 | 0.70x risk for restless legs |
| (G;G) | 1 | normal risk of restless leg syndrome |
| Reference | GRCh38 38.1/141 |
| Chromosome | 15 |
| Position | 67802747 |
| Gene | MAP2K5 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs1026732 |
| dbSNP (classic) | rs1026732 |
| ClinGen | rs1026732 |
| ebi | rs1026732 |
| HLI | rs1026732 |
| Exac | rs1026732 |
| Gnomad | rs1026732 |
| Varsome | rs1026732 |
| LitVar | rs1026732 |
| Map | rs1026732 |
| PheGenI | rs1026732 |
| Biobank | rs1026732 |
| 1000 genomes | rs1026732 |
| hgdp | rs1026732 |
| ensembl | rs1026732 |
| geneview | rs1026732 |
| scholar | rs1026732 |
| rs1026732 | |
| pharmgkb | rs1026732 |
| gwascentral | rs1026732 |
| openSNP | rs1026732 |
| 23andMe | rs1026732 |
| SNPshot | rs1026732 |
| SNPdbe | rs1026732 |
| MSV3d | rs1026732 |
| GWAS Ctlg | rs1026732 |
| GMAF | 0.4913 |
| Max Magnitude | 2 |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
rs1026732, a SNP located in a region of chromosome 15q, has been linked to a lower frequency of restless legs syndrome, a common sleep disorder, with an overall odds ratio of 0.70 (CI: 0.59-0.82) for the (A) minor allele. [PMID 17637780]
[PMID 19279021
] Replication of restless legs syndrome loci in three European populations.
[PMID 20396431] Genotyping sleep disorders patients.
