rs1046089

Orientation

plus

Stabilized

plus

Geno	Mag	Summary
(A;A)		normal
(A;G)		normal
(G;G)		0.48x risk of malaria

Reference

GRCh38 38.1/141

Chromosome

6

Position

31635190

Gene

PRRC2A

is a	snp
is	mentioned by
dbSNP	rs1046089
dbSNP (classic)	rs1046089
ClinGen	rs1046089
ebi	rs1046089
HLI	rs1046089
Exac	rs1046089
Gnomad	rs1046089
Varsome	rs1046089
LitVar	rs1046089
Map	rs1046089
PheGenI	rs1046089
Biobank	rs1046089
1000 genomes	rs1046089
hgdp	rs1046089
ensembl	rs1046089
geneview	rs1046089
scholar	rs1046089
google	rs1046089
pharmgkb	rs1046089
gwascentral	rs1046089
openSNP	rs1046089
23andMe	rs1046089
SNPshot	rs1046089
SNPdbe	rs1046089
MSV3d	rs1046089
GWAS Ctlg	rs1046089

GMAF

0.3944

Max Magnitude

0

?	(A;A) (A;G) (G;G)	28

rs1046089 is a SNP in the HLA-B associated transcript 2 BAT2 gene.

A study of 2,162 case-controls found an association between rs1046089 and severe malaria.[PMID 19039607]

GWAS snp
PMID	[PMID 22267201]
Trait
Title	Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways.
Risk Allele	A
P-val	2E-16
Odds Ratio	0.2130 None

[PMID 18204098] Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX.

[PMID 19143815] MHC fine mapping of human type 1 diabetes using the T1DGC data.

GWAS snp
PMID	[PMID 23307926]
Trait	Menopause (age at onset)
Title	A genome-wide association study of early menopause and the combined impact of identified variants.
Risk Allele	A
P-val	4E-11
Odds Ratio	.19 [0.13-0.25] years increase

GWAS snp
PMID	[PMID 23571483]
Trait	Schizophrenia
Title	A comprehensive family-based replication study of schizophrenia genes.
Risk Allele	G
P-val	4E-6
Odds Ratio	1.30 [NR]

GWAS snp
PMID	[PMID 23894747]
Trait	Schizophrenia
Title	A comprehensive family-based replication study of schizophrenia genes.
Risk Allele	G
P-val	4E-6
Odds Ratio	1.30 [NR]

[PMID 33497044] Genetic Determinants of Premature Menopause in A Mashhad Population Cohort.