rs1047840

Orientation

plus

Stabilized

plus

Make rs1047840(A;A)

Make rs1047840(A;G)

Make rs1047840(G;G)

Reference

GRCh38 38.1/141

Chromosome

1

Position

241878999

Gene

EXO1

is a	snp
is	mentioned by
dbSNP	rs1047840
dbSNP (classic)	rs1047840
ClinGen	rs1047840
ebi	rs1047840
HLI	rs1047840
Exac	rs1047840
Gnomad	rs1047840
Varsome	rs1047840
LitVar	rs1047840
Map	rs1047840
PheGenI	rs1047840
Biobank	rs1047840
1000 genomes	rs1047840
hgdp	rs1047840
ensembl	rs1047840
geneview	rs1047840
scholar	rs1047840
google	rs1047840
pharmgkb	rs1047840
gwascentral	rs1047840
openSNP	rs1047840
23andMe	rs1047840
SNPshot	rs1047840
SNPdbe	rs1047840
MSV3d	rs1047840
GWAS Ctlg	rs1047840

GMAF

0.3609

Max Magnitude

0

?

(A;A) (A;G) (G;G)

28

rs1047840, also known as K589E, is a SNP in the EXO1 gene.

A study of 1,272 breast cancer Taiwanese patients concluded that the rs1047840(A) allele conferred a significantly (p=0.000025) increased risk of breast cancer.[PMID 19846925]

[PMID 19515603] Interaction of Exo1 genotypes and smoking habit in oral cancer in Taiwan

[PMID 20337148] Single-nucleotide polymorphism of the Exo1 gene: association with gastric cancer susceptibility and interaction with smoking in Taiwan

[PMID 22146767] A Single Nucleotide Polymorphism in EXO1 Gene is Associated With Cervical Cancer Susceptibility in Chinese Patients

[PMID 22573488] EGFR exon 19 in-frame deletion and polymorphisms of DNA repair genes in never-smoking female lung adenocarcinoma patients

[PMID 18079015] Potentially functional polymorphisms of EXO1 and risk of lung cancer in a Chinese population: A case-control analysis.

[PMID 18191955 ] Correlating observed odds ratios from lung cancer case-control studies to SNP functional scores predicted by bioinformatic tools.

[PMID 18559551 ] Pathway analysis of single-nucleotide polymorphisms potentially associated with glioblastoma multiforme susceptibility using random forests.

[PMID 19331228] Lung cancer susceptibility and genetic polymorphisms of Exo1 gene in Taiwan.

[PMID 32606887 ] The Impact of the Genetic Polymorphism in DNA Repair Pathways on Increased Risk of Glioblastoma Multiforme in the Arab Jordanian Population: A Case-Control Study.