| Geno
|
Mag
|
Summary
|
| (C;C)
|
1
|
Normal risk for Coronary artery disease
|
| (C;T)
|
1.5
|
1.30x increased risk for Coronary artery disease
|
| (T;T)
|
2
|
1.54x increased risk for Coronary artery disease
|
| Rs10757272
|
| PubMed
|
[PMID 17478681 ]
|
| Affy Probeset
|
SNP_A-2027423
|
| Affy Orientation
|
reverse
|
| On GW 5.0
|
1
|
| Alleles A/B
|
A/G
|
| Ancestral
|
C
|
| Population
|
CEU
|
| Allele
|
T
|
| Case Freq.
|
|
| Control Freq.
|
|
| Odds Ratio Het
|
1.30
|
| Odds Ratio Hom
|
1.54
|
| Odds Ratio All
|
1.23
|
| Disease
|
Coronary artery disease (CAD)
|
rs10757272 increases susceptibility to Coronary artery disease 1.30 times for heterozygotes (CT) and 1.54 times for homozygotes (TT) [PMID 17478681]
[PMID 22286173] Genome-wide association study for intracranial aneurysm in Japanese population identifies three candidate susceptible loci and a functional genetic variant at EDNRA
[PMID 18704761] Molecular genetics of myocardial infarction.
[PMID 20502693] Genetics and beyond--the transcriptome of human monocytes and disease susceptibility.
[PMID 29228923] CDKN2BAS gene polymorphisms and the risk of intracranial aneurysm in the Chinese population.
[PMID 31543200] Genetic variants of chromosome 9p21.3 region associated with coronary artery disease and premature coronary artery disease in an Asian Indian population.
[PMID 30921371] Genome-wide association study of coronary artery calcification in asymptomatic Korean populations.
[PMID 33285697] The association of CDKN2BAS gene polymorphisms and intracranial aneurysm: A meta-analysis.
]
