rs10774671
| Orientation | plus |
| Stabilized | plus |
| Make rs10774671(A;A) |
| Make rs10774671(A;G) |
| Make rs10774671(G;G) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 12 |
| Position | 112919388 |
| Gene | OAS1 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs10774671 |
| dbSNP (classic) | rs10774671 |
| ClinGen | rs10774671 |
| ebi | rs10774671 |
| HLI | rs10774671 |
| Exac | rs10774671 |
| Gnomad | rs10774671 |
| Varsome | rs10774671 |
| LitVar | rs10774671 |
| Map | rs10774671 |
| PheGenI | rs10774671 |
| Biobank | rs10774671 |
| 1000 genomes | rs10774671 |
| hgdp | rs10774671 |
| ensembl | rs10774671 |
| geneview | rs10774671 |
| scholar | rs10774671 |
| rs10774671 | |
| pharmgkb | rs10774671 |
| gwascentral | rs10774671 |
| openSNP | rs10774671 |
| 23andMe | rs10774671 |
| SNPshot | rs10774671 |
| SNPdbe | rs10774671 |
| MSV3d | rs10774671 |
| GWAS Ctlg | rs10774671 |
| GMAF | 0.3604 |
| Max Magnitude | 0 |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
[PMID 19247438
] Genetic variation in OAS1 is a risk factor for initial infection with West Nile virus in man.
[PMID 19799013] Analysis of the nicastrin promoter rs10752637 polymorphism and its association with Alzheimer's disease
[PMID 19956105] Reassessment of the type I diabetes association of the OAS1 locus
[PMID 21939710] Genetic polymorphisms in host antiviral genes: Associations with humoral and cellular immunity to measles vaccine
[PMID 22710942] Evaluate the relationship between polymorphisms of OAS1 gene and susceptibility to chronic hepatitis C with high resolution melting analysis
[PMID 16014697] Type 1 diabetes and the OAS gene cluster: association with splicing polymorphism or haplotype?
[PMID 16644715] No evidence for association of OAS1 with type 1 diabetes in unaffected siblings or type 1 diabetic cases.
[PMID 18518984] Genome-wide survey of allele-specific splicing in humans.
[PMID 19956101] Overview of the Rapid Response data.
[PMID 19956106] Analysis of 19 genes for association with type I diabetes in the Type I Diabetes Genetics Consortium families.
[PMID 19956109] The Type I Diabetes Genetics Consortium 'Rapid Response' family-based candidate gene study: strategy, genes selection, and main outcome.
[PMID 20195503] Genome-wide mRNA expression correlates of viral control in CD4+ T-cells from HIV-1-infected individuals.
[PMID 21735172] Identification of a new susceptibility variant for multiple sclerosis in OAS1 by population genetics analysis.
[PMID 23220500] Differential effects of a common splice site polymorphism on the generation of OAS1 variants in human bronchial epithelial cells.
[PMID 23337612] Polymorphisms in the oligoadenylate synthetase gene cluster and its association with clinical outcomes of dengue virus infection.
[PMID 25205466] Mitochondrial localization of the OAS1 p46 isoform associated with a common single nucleotide polymorphism
| ClinVar | |
|---|---|
| Risk | rs10774671(A;A) |
| Alt | rs10774671(A;A) |
| Reference | rs10774671(G;G) |
| Significance | Other |
| Disease | Diabetes mellitus |
| Variation | info |
| Gene | OAS1 |
| CLNDBN | Diabetes mellitus, type 1, susceptibility to |
| Reversed | 0 |
| HGVS | NC_000012.11:g.113357193G\x3d |
| CLNSRC | OMIM Allelic Variant |
| CLNACC | RCV000015021.2, |
[PMID 26412166] [A case-control study on association between OAS1 polymorphism and susceptibility to spontaneous preterm birth and preterm premature rupture of membranes]
