rs10868366
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 0 | |
| (G;G) | 0 | average |
| (G;T) | reduced risk for AD? | |
| (T;T) | reduced risk for AD? |
| Reference | GRCh38 38.1/141 |
| Chromosome | 9 |
| Position | 86085145 |
| Gene | GOLM1 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs10868366 |
| dbSNP (classic) | rs10868366 |
| ClinGen | rs10868366 |
| ebi | rs10868366 |
| HLI | rs10868366 |
| Exac | rs10868366 |
| Gnomad | rs10868366 |
| Varsome | rs10868366 |
| LitVar | rs10868366 |
| Map | rs10868366 |
| PheGenI | rs10868366 |
| Biobank | rs10868366 |
| 1000 genomes | rs10868366 |
| hgdp | rs10868366 |
| ensembl | rs10868366 |
| geneview | rs10868366 |
| scholar | rs10868366 |
| rs10868366 | |
| pharmgkb | rs10868366 |
| gwascentral | rs10868366 |
| openSNP | rs10868366 |
| 23andMe | rs10868366 |
| SNPshot | rs10868366 |
| SNPdbe | rs10868366 |
| MSV3d | rs10868366 |
| GWAS Ctlg | rs10868366 |
| GMAF | 0.3205 |
| Max Magnitude | 0 |
| ? | (G;G) (G;T) (T;T) | 28 |
|---|---|---|
|
| ||
rs10868366, a SNP in the GOLM1 gene, is associated with reduced risk for Alzheimer's disease in a study of ~1100 Canadian patients. The protective allele appears to be rs10868366(T), giving an odds ratio of 0.55 (CI: 0.40 - 0.75). [PMID 17998437]
[PMID 20570408] Genetic variation in GOLM1 and prefrontal cortical volume in Alzheimer's disease
[PMID 19749441] GOLPH2 gene markers are not associated with Alzheimer's disease in a sample of the Spanish population.
[PMID 20574532
] Intermediate phenotypes identify divergent pathways to Alzheimer's disease.
[PMID 22167654] Association studies of 19 candidate SNPs with sporadic Alzheimer's disease in the North Chinese Han population.
