rs110402

Orientation

minus

Stabilized

minus

Make rs110402(C;C)

Make rs110402(C;T)

Make rs110402(T;T)

Reference

GRCh38 38.1/141

Chromosome

17

Position

45802681

Gene	CRHR1, CRHR1-IT1-CRHR1

is a	snp
is	mentioned by
dbSNP	rs110402
dbSNP (classic)	rs110402
ClinGen	rs110402
ebi	rs110402
HLI	rs110402
Exac	rs110402
Gnomad	rs110402
Varsome	rs110402
LitVar	rs110402
Map	rs110402
PheGenI	rs110402
Biobank	rs110402
1000 genomes	rs110402
hgdp	rs110402
ensembl	rs110402
geneview	rs110402
scholar	rs110402
google	rs110402
pharmgkb	rs110402
gwascentral	rs110402
openSNP	rs110402
23andMe	rs110402
SNPshot	rs110402
SNPdbe	rs110402
MSV3d	rs110402
GWAS Ctlg	rs110402

GMAF

0.4628

Max Magnitude

0

?	(C;C) (C;T) (T;T)	28

[PMID 19596121] Interaction of Childhood Maltreatment with the Corticotropin-Releasing Hormone Receptor Gene: Effects on Hypothalamic-Pituitary-Adrenal Axis Reactivity

[PMID 19736354] Protective effect of CRHR1 gene variants on the development of adult depression following childhood maltreatment: replication and extension

[PMID 20029939] Polymorphisms in CRHR1 and the serotonin transporter loci: gene x gene x environment interactions on depressive symptoms

[PMID 22378896] Variation in the Corticotropin-Releasing Hormone Receptor 1 (CRHR1) Gene Influences fMRI Signal Responses during Emotional Stimulus Processing.

[PMID 15297935] Linkage disequilibrium and association of MAPT H1 in Parkinson disease.

[PMID 17467808] Genetic variability at HPA axis in major depression and clinical response to antidepressant treatment.

[PMID 18250257] Influence of child abuse on adult depression: moderation by the corticotropin-releasing hormone receptor gene.

[PMID 18349090] Association of FKBP5 polymorphisms and childhood abuse with risk of posttraumatic stress disorder symptoms in adults.

[PMID 19750552] Risk and resilience: genetic and environmental influences on development of the stress response.

[PMID 19772600] A comparison of classification methods for predicting Chronic Fatigue Syndrome based on genetic data.

[PMID 20161813] Effect of Childhood Trauma on Adult Depression and Neuroendocrine Function: Sex-Specific Moderation by CRH Receptor 1 Gene.

[PMID 21172166] Pharmacogenetics of antidepressant response.

[PMID 21438878] Moderation of the association between childhood maltreatment and neuroticism by the corticotropin-releasing hormone receptor 1 gene.

[PMID 21810631] Prediction of the risk of comorbid alcoholism in schizophrenia by interaction of common genetic variants in the corticotropin-releasing factor system.

[PMID 22467522] Association of CRHR1 and CRHR2 with major depressive disorder and panic disorder in a Japanese population.

[PMID 23274505] Genetic association of FKBP5 and CRHR1 with cortisol response to acute psychosocial stress in healthy adults

[PMID 24623788] Indirect Effect of Corticotropin-Releasing Hormone Receptor 1 Gene Variation on Negative Emotionality and Alcohol Use via Right Ventrolateral Prefrontal Cortex

[PMID 22748421] Interactive effects of corticotropin-releasing hormone receptor 1 gene and childhood adversity on depressive symptoms in young adults: findings from a longitudinal study.

[PMID 23294766] Behavioral, biological, and chemical perspectives on targeting CRF(1) receptor antagonists to treat alcoholism.

[PMID 23473364] The CRHR1 gene, trauma exposure, and alcoholism risk: a test of G x E effects.

[PMID 26543368] Epidemiological support for genetic variability at hypothalamic-pituitary-adrenal axis and serotonergic system as risk factors for major depression

[PMID 27894002] Polymorphism in CRHR1 gene affects the IL-1β levels in suicidal attempters.

[PMID 30949563] FAAH genotype, CRFR1 genotype, and cortisol interact to predict anxiety in an aging, rural Hispanic population: A Project FRONTIER study.

[PMID 32361186] Salivary cortisol response to psychosocial stress in the late evening depends on CRHR1 genotype.

[PMID 32697690] Interactions of childhood maltreatment and genetic variations in adult depression: A systematic review.