rs11045818

Orientation

plus

Stabilized

plus

Geno	Mag	Summary
(G;G)	0	common in clinvar

Make rs11045818(A;A)

Make rs11045818(A;G)

Reference

GRCh38.p2 38.2/144

Chromosome

12

Position

21176827

Gene

SLCO1B1

is a	snp
is	mentioned by
dbSNP	rs11045818
dbSNP (classic)	rs11045818
ClinGen	rs11045818
ebi	rs11045818
HLI	rs11045818
Exac	rs11045818
Gnomad	rs11045818
Varsome	rs11045818
LitVar	rs11045818
Map	rs11045818
PheGenI	rs11045818
Biobank	rs11045818
1000 genomes	rs11045818
hgdp	rs11045818
ensembl	rs11045818
geneview	rs11045818
scholar	rs11045818
google	rs11045818
pharmgkb	rs11045818
gwascentral	rs11045818
openSNP	rs11045818
23andMe	rs11045818
SNPshot	rs11045818
SNPdbe	rs11045818
MSV3d	rs11045818
GWAS Ctlg	rs11045818

Max Magnitude

0

?	(A;A) (A;G) (G;G)	28

GWAS snp
PMID	[PMID 19901119]
Trait	Methotrexate phramacokinetics (acute lymphoblastic leukemia)
Title	Germline genetic variation in an organic anion transporter polypeptide associated with methotrexate pharmacokinetics and clinical effects.
Risk Allele	G
P-val	7E-7
Odds Ratio	9.30 [5.7-12.9] mL/min/m2 decrease

ClinVar
Risk	rs11045818(A;A)
Alt	rs11045818(A;A)
Reference	Rs11045818(G;G)
Significance	Probable-non-pathogenic
Disease	Rotor syndrome
Variation	info
Gene	SLCO1B1
CLNDBN	Rotor syndrome
Reversed	0
HGVS	NC_000012.11:g.21329761G>A
CLNSRC
CLNACC	RCV000310218.1,