rs11110912
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 0 | common/normal |
| (C;G) | 0.1 | Maybe some quite minor increase in high blood pressure risk; data not replicated though |
| (G;G) | 0.1 | Maybe some quite minor increase in high blood pressure risk; data not replicated though |
| Reference | GRCh38 38.1/141 |
| Chromosome | 12 |
| Position | 101648435 |
| Gene | LOC105369937, MYBPC1 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs11110912 |
| dbSNP (classic) | rs11110912 |
| ClinGen | rs11110912 |
| ebi | rs11110912 |
| HLI | rs11110912 |
| Exac | rs11110912 |
| Gnomad | rs11110912 |
| Varsome | rs11110912 |
| LitVar | rs11110912 |
| Map | rs11110912 |
| PheGenI | rs11110912 |
| Biobank | rs11110912 |
| 1000 genomes | rs11110912 |
| hgdp | rs11110912 |
| ensembl | rs11110912 |
| geneview | rs11110912 |
| scholar | rs11110912 |
| rs11110912 | |
| pharmgkb | rs11110912 |
| gwascentral | rs11110912 |
| openSNP | rs11110912 |
| 23andMe | rs11110912 |
| SNPshot | rs11110912 |
| SNPdbe | rs11110912 |
| MSV3d | rs11110912 |
| GWAS Ctlg | rs11110912 |
| GMAF | 0.1061 |
| Max Magnitude | 0.1 |
| ? | (C;C) (C;G) (G;G) | 28 |
|---|---|---|
|
| ||
rs11110912 was reported in a 2007 study to be associated with high blood pressure.
The risk allele (oriented to the dbSNP entry) is (G); the odds ratio associated with heterozygotes is 1.33 (CI 1.18-1.51), and for homozygotes, 1.34 (CI 0.96-1.86). [PMID 17554300
]
[PMID 18523456] Replication of the Wellcome Trust genome-wide association study of essential hypertension: the Family Blood Pressure Program. Note: rs11110912 did not replicate in this 2008 study.
