rs11200014

plus

Geno	Mag	Summary
(A;A)		1.64x risk for breast cancer
(A;G)		1.20x risk for breast cancer
(G;G)		common

Reference

GRCh38 38.1/142

Chromosome

10

Position

121575416

Gene

FGFR2

is a	snp
is	mentioned by
dbSNP	rs11200014
dbSNP (classic)	rs11200014
ClinGen	rs11200014
ebi	rs11200014
HLI	rs11200014
Exac	rs11200014
Gnomad	rs11200014
Varsome	rs11200014
LitVar	rs11200014
Map	rs11200014
PheGenI	rs11200014
Biobank	rs11200014
1000 genomes	rs11200014
hgdp	rs11200014
ensembl	rs11200014
geneview	rs11200014
scholar	rs11200014
google	rs11200014
pharmgkb	rs11200014
gwascentral	rs11200014
openSNP	rs11200014
23andMe	rs11200014
SNPshot	rs11200014
SNPdbe	rs11200014
MSV3d	rs11200014
GWAS Ctlg	rs11200014

GMAF

0.3379

Max Magnitude

0

?

(A;A) (A;G) (G;G)

28

This SNP is basically a proxy for SNP rs1219648, which represents the SNP in the FGFR2 gene with the strongest association with breast cancer. [PMID 17529973 ]

[PMID 18285324 ] Common variation in the fibroblast growth factor receptor 2 gene is not associated with endometriosis risk.

[PMID 19223389 ] FGFR2 variants and breast cancer risk: fine-scale mapping using African American studies and analysis of chromatin conformation.

[PMID 19497954 ] Histone-acetylated control of fibroblast growth factor receptor 2 intron 2 polymorphisms and isoform splicing in breast cancer.

[PMID 19500394 ] Genetic variants in FGFR2 and FGFR4 genes and skin cancer risk in the Nurses' Health Study.

[PMID 20554749 ] FGFR2 and other loci identified in genome-wide association studies are associated with breast cancer in African-American and younger women.

[PMID 22965832] Association of common genetic variants with breast cancer risk and clinicopathological characteristics in a Chinese population.

[PMID 23124475] Three novel functional polymorphisms in the promoter of FGFR2 gene and breast cancer risk: a HuGE review and meta-analysis.