rs121964874

Orientation

plus

Stabilized

plus

Geno	Mag	Summary
(C;C)	0	common in clinvar
(C;T)	6.7	CDH1-based gastric cancer risk

Make rs121964874(T;T)

Reference

GRCh38 38.1/141

Chromosome

16

Position

68823557

Gene

CDH1

is a	snp
is	mentioned by
dbSNP	rs121964874
dbSNP (classic)	rs121964874
ClinGen	rs121964874
ebi	rs121964874
HLI	rs121964874
Exac	rs121964874
Gnomad	rs121964874
Varsome	rs121964874
LitVar	rs121964874
Map	rs121964874
PheGenI	rs121964874
Biobank	rs121964874
1000 genomes	rs121964874
hgdp	rs121964874
ensembl	rs121964874
geneview	rs121964874
scholar	rs121964874
google	rs121964874
pharmgkb	rs121964874
gwascentral	rs121964874
openSNP	rs121964874
23andMe	rs121964874
SNPshot	rs121964874
SNPdbe	rs121964874
MSV3d	rs121964874
GWAS Ctlg	rs121964874

Max Magnitude

6.7

Also known as c.2095C>T or p.Gln699Ter, the minor allele is considered a pathogenic rare mutation for hereditary diffuse gastric cancer in ClinVar.

OMIM	192090
Desc
Variant	0007
Related	also

ClinVar
Risk	rs121964874(A;A) rs121964874(G;G) rs121964874(T;T)
Alt	rs121964874(A;A) rs121964874(G;G) rs121964874(T;T)
Reference	Rs121964874(C;C)
Significance	Pathogenic
Disease	Hereditary cancer-predisposing syndrome Hereditary diffuse gastric cancer
Variation	info
Gene	CDH1
CLNDBN	Hereditary cancer-predisposing syndrome Hereditary diffuse gastric cancer
Reversed	0
HGVS	NC_000016.9:g.68857460C>G; NC_000016.9:g.68857460C>T
CLNSRC	OMIM Allelic Variant
CLNACC	RCV000132483.2, RCV000013024.25,