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CDH1

From SNPedia
is agene
is mentioned by
Full namecadherin 1, type 1, E-cadherin (epithelial)
EntrezGene999
PheGenI999
VariationViewer999
ClinVarCDH1
GeneCardsCDH1
dbSNP999
DiseasesCDH1
SADR999
HugeNav999
wikipediaCDH1_(gene)
googleCDH1
gopubmedCDH1
EVSCDH1
HEFalMpCDH1
MyGene2CDH1
23andMeCDH1
UniProtP12830
EnsemblENSG00000039068
OMIM192090
# SNPs124
 Max MagnitudeChromosome positionSummary
i5004969
i5004970
i5004971
i5004972
i5004974
i5004975
i5994973
rs10431923068,805,360
rs10431924068,805,399
rs1057517542068,829,653
rs1060501214068,810,205
rs1060501215068,801,883
rs1060501224068,822,184
rs1060501226068,738,295
rs1060501237068,811,861
rs1060501244068,828,204
rs1060501248068,829,682
rs1064794230068,808,525
rs1064795267068,815,760
rs1064795703068,801,821
rs116093741568,812,144
rs11642413068,756,491
rs12185157068,750,684
rs121964871068,823,593
rs121964872068,833,362
rs1219648736.768,810,290
rs1219648746.768,823,557
rs121964875568,738,307
rs1219648766.768,738,318
rs1219648776.768,822,081
rs121964878568,822,190
rs12597188068,780,923
rs13689068,834,619
rs16260068,737,131
rs16958383068,823,097
rs17690554068,835,607
rs17715799068,796,608
rs1801026068,833,553
rs1801552068,823,538
rs1862748068,799,040
rs202115589068,819,424
rs2676067126.768,811,859
rs28372783068,737,219
rs33935154068,822,138
rs35572355568,833,344
rs370345996068,829,757
rs376152506068,801,888
rs4783573068,806,685
rs4783673068,758,190
rs4783689068,819,768
... further results


The CDH1 gene encodes the cadherin-1 protein, also known as CAM 120/80 or epithelial cadherin (E-cadherin). It is a tumor suppressor gene, and mutations in this gene have been associated with various cancers including breast cancer and hereditary diffuse gastric cancer.

Mutations considered pathogenic and acting in a dominant manner for gastric cancer, hereditary cancer-predisposing syndrome and related cancers include:

rsid 23andMe term synonyms (c. or p.) OMIM On chip?
rs572272864 c.-63C>A
rs749591910 c.48+5G>C
rs121964875 i5004971 c.59G>A 192090.0009 Ancestry v2, Ancestry v2c, Ancestry v2d
rs786203576 i5004970 c.60G>A
rs121964876 i5004972 c.70G>T 192090.0011 Ancestry v2, Ancestry v2d
rs786201058 c.76G>T
rs876658865 c.124_126delCCCinsT
rs786203727 c.185G>T
rs587783047 c.187C>T Ancestry v2, 23andMe v5, Ancestry v2c, Ancestry v2d
rs786202151 c.202delT 23andMe v5, Ancestry v2c, Ancestry v2d
rs781409616 c.283C>T
rs587782677 c.353C>G Ancestry v2, Ancestry v2d
rs746703615 c.377delC
rs376152506 c.382delC
rs864622655 c.504delA Ancestry v2c, Ancestry v2d
rs587780537 c.715G>A Ancestry v2, 23andMe v5, Ancestry v2c, Ancestry v2d
rs587780784 c.1003C>T 23andMe v5, Ancestry v2c, Ancestry v2d
rs267606712 c.1008G>T 192090.0005 Ancestry v2, Ancestry v2c, Ancestry v2d
rs786201045 c.1009_1010delAG
rs116093741 i5004975 c.1018A>G 192090.0016 Ancestry v2, Ancestry v2d
rs587776398 c.1023T>G Ancestry v2c, Ancestry v2d
rs863224505 c.1063delT Ancestry v2c, Ancestry v2d
rs869312764 c.1064delT
rs587782359 c.1118C>T Ancestry v2, 23andMe v5, Ancestry v2c, Ancestry v2d
rs587783050 c.1137G>A Ancestry v2, 23andMe v5, Ancestry v2c, Ancestry v2d
rs876660771 c.1137+1G>A 23andMe v5, Ancestry v2c, Ancestry v2d
rs587782798 c.1147C>T Ancestry v2, 23andMe v5, Ancestry v2c, Ancestry v2d
rs876659208 c.1476_1477delAG
rs876658261 c.1488_1494delCGAGGAC
rs869312765 c.1505delG
rs587780113 c.1565+1G>T Ancestry v2c, Ancestry v2d
rs587780113 c.1565+1G>A Ancestry v2c, Ancestry v2d
rs730881667 c.1610delC Ancestry v2, Ancestry v2c, Ancestry v2d
rs202115589 c.1710delT Ancestry v2c, Ancestry v2d
rs786202290 c.1711+5G>A 23andMe v5, Ancestry v2c, Ancestry v2d
rs121964877 i5994973 c.1792C>T 192090.0012 Ancestry v2, Ancestry v2c, Ancestry v2d
rs121964878 i5004974 c.1901C>T 192090.0015 Ancestry v2, Ancestry v2d
rs587782750 c.1921C>T Ancestry v2, 23andMe v5, Ancestry v2c, Ancestry v2d
rs730881653 c.1979dupT Ancestry v2, 23andMe v5, Ancestry v2c, Ancestry v2d
rs786202033 c.1999delC Ancestry v2c, Ancestry v2d
rs587781276 c.2064_2065delTG 23andMe v5
rs121964874 i5004969 c.2095C>T 192090.0007 Ancestry v2, Ancestry v2c, Ancestry v2d
rs776975632 c.2245C>T
rs587780787 c.2287G>T Ancestry v2, 23andMe v5, Ancestry v2c, Ancestry v2d
rs754162869 c.2310delC
rs587780119 c.2343A>T
rs587781335 c.2396C>G Ancestry v2, Ancestry v2c, Ancestry v2d
rs587783048 c.2398delC Ancestry v2, 23andMe v5, Ancestry v2c, Ancestry v2d
rs370345996 c.2399delG Ancestry v2, Ancestry v2c, Ancestry v2d
rs786203752 c.2430delT 23andMe v5
rs35572355 rs35572355 c.2494G>A 192090.0017 23andMe v4, Ancestry v2, 23andMe v5, Ancestry v2c, 23andMe v3, 23andMe v1, Ancestry v2d