rs121964877

plus

Geno	Mag	Summary
(C;C)	0	common in clinvar
(C;T)	6.7	CDH1-based gastric cancer risk

Make rs121964877(T;T)

Reference

GRCh38 38.1/141

Chromosome

16

Position

68822081

Gene

CDH1

is a	snp
is	mentioned by
dbSNP	rs121964877
dbSNP (classic)	rs121964877
ClinGen	rs121964877
ebi	rs121964877
HLI	rs121964877
Exac	rs121964877
Gnomad	rs121964877
Varsome	rs121964877
LitVar	rs121964877
Map	rs121964877
PheGenI	rs121964877
Biobank	rs121964877
1000 genomes	rs121964877
hgdp	rs121964877
ensembl	rs121964877
geneview	rs121964877
scholar	rs121964877
google	rs121964877
pharmgkb	rs121964877
gwascentral	rs121964877
openSNP	rs121964877
23andMe	rs121964877
SNPshot	rs121964877
SNPdbe	rs121964877
MSV3d	rs121964877
GWAS Ctlg	rs121964877

Max Magnitude

6.7

Also known as c.1792C>T, p.Arg598Ter and R598X, the minor allele is considered a pathogenic rare mutation for hereditary diffuse gastric cancer in ClinVar.

OMIM	192090
Desc
Variant	0012
Related	also

ClinVar
Risk	rs121964877(G;G) rs121964877(T;T)
Alt	rs121964877(G;G) rs121964877(T;T)
Reference	Rs121964877(C;C)
Significance	Pathogenic
Disease	Hereditary diffuse gastric cancer Hereditary cancer-predisposing syndrome not provided
Variation	info
Gene	CDH1
CLNDBN	Hereditary diffuse gastric cancer Hereditary cancer-predisposing syndrome not provided
Reversed	0
HGVS	NC_000016.9:g.68855984C>G; NC_000016.9:g.68855984C>T
CLNSRC	OMIM Allelic Variant
CLNACC	RCV000470902.1, RCV000013028.24, RCV000213248.1, RCV000484230.1,