rs12777823
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | 3.5 | Avoid Plavix, higher risk for adverse cardiovascular events. CYP2C19 poor metabolizer. |
| (A;G) | 2.5 | Avoid Plavix, higher risk for adverse cardiovascular events. |
| (G;G) | 0 | common in clinvar |
| Reference | GRCh38 38.1/142 |
| Chromosome | 10 |
| Position | 94645745 |
| Gene | LOC100130970 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs12777823 |
| dbSNP (classic) | rs12777823 |
| ClinGen | rs12777823 |
| ebi | rs12777823 |
| HLI | rs12777823 |
| Exac | rs12777823 |
| Gnomad | rs12777823 |
| Varsome | rs12777823 |
| LitVar | rs12777823 |
| Map | rs12777823 |
| PheGenI | rs12777823 |
| Biobank | rs12777823 |
| 1000 genomes | rs12777823 |
| hgdp | rs12777823 |
| ensembl | rs12777823 |
| geneview | rs12777823 |
| scholar | rs12777823 |
| rs12777823 | |
| pharmgkb | rs12777823 |
| gwascentral | rs12777823 |
| openSNP | rs12777823 |
| 23andMe | rs12777823 |
| SNPshot | rs12777823 |
| SNPdbe | rs12777823 |
| MSV3d | rs12777823 |
| GWAS Ctlg | rs12777823 |
| GMAF | 0.2213 |
| Max Magnitude | 3.5 |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
JAMA rs12777823 and rs4244285 implicated in platelet response to clopidogrel
[PMID 19706858
] Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy
[PMID 23755828] Genetic variants associated with warfarin dose in African-American individuals: a genome-wide association study
| ClinVar | |
|---|---|
| Risk | Rs12777823(A;A) |
| Alt | Rs12777823(A;A) |
| Reference | Rs12777823(G;G) |
| Significance | Drug-response |
| Disease | warfarin response - Dosage |
| Variation | info |
| Gene | |
| CLNDBN | warfarin response - Dosage |
| Reversed | 0 |
| HGVS | NC_000010.10:g.96405502G>A |
| CLNSRC | PharmGKB Clinical Annotation |
| CLNACC | RCV000211190.1, |
