5,261 obese individuals with 14,106 controls, all of European descent. This snp is in on the 23andMe microarray, and reported as equivalent to ones reported in [PMID 19079261
] and [PMID 21912638]. (T;T) linked to 1.12 times higher odds of obesity compared to individuals with the (C;T) genotype, and those with the (C;C) genotype had about 1.12 times lower odds of obesity.
[PMID 19478790] The role of obesity-associated loci identified in genome-wide association studies in the determination of pediatric BMI.
Obesity: Preliminary Research
Measures of Obesity
| GWAS snp
|
| PMID
|
[PMID 23669352]
|
| Trait
|
Body mass index
|
| Title
|
Genome-wide analysis of BMI in adolescents and young adults reveals additional insight into the effects of genetic loci over the life course.
|
| Risk Allele
|
T
|
| P-val
|
6E-9
|
| Odds Ratio
|
.05 [0.032-0.068] unit increase
|
| GWAS snp
|
| PMID
|
[PMID 23563607]
|
| Trait
|
Obesity
|
| Title
|
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.
|
| Risk Allele
|
T
|
| P-val
|
3E-18
|
| Odds Ratio
|
1.14 [NR]
|
[PMID 23408508] Obesity-susceptibility loci and the tails of the pediatric BMI distribution
[PMID 31936053] Effect of 15 BMI-Associated Polymorphisms, Reported for Europeans, across Ethnicities and Degrees of Amerindian Ancestry in Mexican Children.
] and [PMID 21912638
