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rs17121510

From SNPedia

Orientationplus
Stabilizedplus
Make rs17121510(A;A)
Make rs17121510(A;G)
Make rs17121510(G;G)
ReferenceGRCh38 38.1/141
Chromosome11
Position118005440
GeneLOC107984395
is asnp
is mentioned by
dbSNPrs17121510
dbSNP (classic)rs17121510
ClinGenrs17121510
ebirs17121510
HLIrs17121510
Exacrs17121510
Gnomadrs17121510
Varsomers17121510
LitVarrs17121510
Maprs17121510
PheGenIrs17121510
Biobankrs17121510
1000 genomesrs17121510
hgdprs17121510
ensemblrs17121510
geneviewrs17121510
scholarrs17121510
googlers17121510
pharmgkbrs17121510
gwascentralrs17121510
openSNPrs17121510
23andMers17121510
SNPshotrs17121510
SNPdbers17121510
MSV3drs17121510
GWAS Ctlgrs17121510
GMAF0.1446
Max Magnitude0
? (A;A) (A;G) (G;G) 28


A study of maternal and fetal DNA from 370 US Caucasian birth-events (172 cases and 198 controls) concluded that the single strongest effect in fetal DNA was associated with rs17121510 in the interleukin-10 receptor antagonist (IL-10RA) gene at both allelic (p = 0.01) and genotypic (p = 3.34x10e-4) levels. The odds ratio for preterm birth for the genotypic additive model was 1.92 (CI: 1.15-3.19, p = 2.00x10e-3). [PMID 18818748OA-icon.png]

[PMID 20463618OA-icon.png] Role of polymorphic variants as genetic modulators of infection in neonatal sepsis.