rs17125944

Orientation

plus

Stabilized

plus

Make rs17125944(C;C)

Make rs17125944(C;T)

Make rs17125944(T;T)

Reference

GRCh38 38.1/141

Chromosome

14

Position

52933911

Gene

FERMT2

is a	snp
is	mentioned by
dbSNP	rs17125944
dbSNP (classic)	rs17125944
ClinGen	rs17125944
ebi	rs17125944
HLI	rs17125944
Exac	rs17125944
Gnomad	rs17125944
Varsome	rs17125944
LitVar	rs17125944
Map	rs17125944
PheGenI	rs17125944
Biobank	rs17125944
1000 genomes	rs17125944
hgdp	rs17125944
ensembl	rs17125944
geneview	rs17125944
scholar	rs17125944
google	rs17125944
pharmgkb	rs17125944
gwascentral	rs17125944
openSNP	rs17125944
23andMe	rs17125944
SNPshot	rs17125944
SNPdbe	rs17125944
MSV3d	rs17125944
GWAS Ctlg	rs17125944

Max Magnitude

0

?	(C;C) (C;T) (T;T)	28

GWAS snp
PMID	[PMID 24162737]
Trait	Alzheimer's disease (late onset)
Title	Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
Risk Allele	C
P-val	8E-9
Odds Ratio	1.14 [1.09-1.19]

One study found no significant association between the rs17125944 polymorphism and late-onset Alzheimer's disease (LOAD) in a Chinese Han population, with or without stratification by apolipoprotein E (APOE) ε4 genotype and multivariate logistic regression analysis. When the investigators performed a meta-analysis in 81908 individuals including their study population, they confirmed a previously-reported association between the C allele and LOAD in Caucasian subjects (OR = 1.15, 95 % CI = 1.10–1.20) and in the population as a whole, but not in Chinese subjects.

[PMID 27244899] FERMT2 rs17125944 polymorphism with Alzheimer's disease risk: a replication and meta-analysis.

[PMID 24788522] Genetic variation at the CELF1 (CUGBP, elav-like family member 1 gene) locus is genome-wide associated with Alzheimer's disease and obesity

[PMID 26543236] Risk prediction for sporadic Alzheimer's disease using genetic risk score in the Han Chinese population

FERMT2 Is Associated with Brain Amyloidosis in Cognitively Normal and Mild Cognitive Impairment Subjects