rs17145738
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 0 | common on affy axiom data |
| Make rs17145738(C;T) |
| Make rs17145738(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 7 |
| Position | 73568544 |
| Gene | TBL2 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs17145738 |
| dbSNP (classic) | rs17145738 |
| ClinGen | rs17145738 |
| ebi | rs17145738 |
| HLI | rs17145738 |
| Exac | rs17145738 |
| Gnomad | rs17145738 |
| Varsome | rs17145738 |
| LitVar | rs17145738 |
| Map | rs17145738 |
| PheGenI | rs17145738 |
| Biobank | rs17145738 |
| 1000 genomes | rs17145738 |
| hgdp | rs17145738 |
| ensembl | rs17145738 |
| geneview | rs17145738 |
| scholar | rs17145738 |
| rs17145738 | |
| pharmgkb | rs17145738 |
| gwascentral | rs17145738 |
| openSNP | rs17145738 |
| 23andMe | rs17145738 |
| SNPshot | rs17145738 |
| SNPdbe | rs17145738 |
| MSV3d | rs17145738 |
| GWAS Ctlg | rs17145738 |
| GMAF | 0.09688 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
[PMID 18596051] rs17145738 influences severe hypertriglyceridemia. 132 patients of European ancestry with severe HTG (fasting plasma TG>10 mmol/L), and 351 matched normolipidemic controls
| GWAS | |
|---|---|
| SNP | rs17145738 |
| PubMedID | [PMID 18193043 ]
|
| Condition | Triglycerides |
| Gene | MLXIPL |
| Risk Allele | C |
| pValue | 2.00E-012 |
| OR | 8.21 |
| 95% CI | NR) mg/dl highe |
| GWAS snp | |
|---|---|
| PMID | [PMID 18193044]
|
| Trait | Triglycerides |
| Title | Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans |
| Risk Allele | T |
| P-val | 7.0000000000000001E-22 |
| Odds Ratio | 0.14 [0.25-0.53] % SD lower |
[PMID 19656773] A polygenic basis for four classical Fredrickson hyperlipoproteinemia phenotypes that are characterized by hypertriglyceridemia
[PMID 21149302] Effects of genetic variants on lipid parameters and dyslipidemia in a Chinese population
| GWAS snp | |
|---|---|
| PMID | [PMID 20686565]
|
| Trait | |
| Title | Biological, clinical and population relevance of 95 loci for blood lipids. |
| Risk Allele | T |
| P-val | 1E-9 |
| Odds Ratio | 0.5700 None |
[PMID 18852197] Metabolic and cardiovascular traits: an abundance of recently identified common genetic variants.
[PMID 19060910] Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.
[PMID 19185284] Common variation in the beta-carotene 15,15'-monooxygenase 1 gene affects circulating levels of carotenoids: a genome-wide association study.
[PMID 19197348] Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae.
[PMID 19299407] Replication of genetic associations with plasma lipoprotein traits in a multiethnic sample.
[PMID 19435741] Common lipid-altering gene variants are associated with therapeutic intervention thresholds of lipid levels in older people.
[PMID 20017967] Genome-wide association analyses of North American Rheumatoid Arthritis Consortium and Framingham Heart Study data utilizing genome-wide linkage results.
[PMID 20158509] Triglyceride level modifying functional variants of GALTN2 and MLXIPL in patients with ischaemic stroke.
[PMID 24160749] Association of the MLXIPL/TBL2 rs17145738 SNP and serum lipid levels in the Guangxi Mulao and Han populations
| GWAS snp | |
|---|---|
| PMID | [PMID 24097068]
|
| Trait | HDL cholesterol |
| Title | Discovery and refinement of loci associated with lipid levels. |
| Risk Allele | T |
| P-val | 5E-13 |
| Odds Ratio | .04 [NR] unit increase |
