rs174583
| Orientation | plus |
| Stabilized | plus |
| Make rs174583(C;C) |
| Make rs174583(C;T) |
| Make rs174583(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 11 |
| Position | 61842278 |
| Gene | FADS2 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs174583 |
| dbSNP (classic) | rs174583 |
| ClinGen | rs174583 |
| ebi | rs174583 |
| HLI | rs174583 |
| Exac | rs174583 |
| Gnomad | rs174583 |
| Varsome | rs174583 |
| LitVar | rs174583 |
| Map | rs174583 |
| PheGenI | rs174583 |
| Biobank | rs174583 |
| 1000 genomes | rs174583 |
| hgdp | rs174583 |
| ensembl | rs174583 |
| geneview | rs174583 |
| scholar | rs174583 |
| rs174583 | |
| pharmgkb | rs174583 |
| gwascentral | rs174583 |
| openSNP | rs174583 |
| 23andMe | rs174583 |
| SNPshot | rs174583 |
| SNPdbe | rs174583 |
| MSV3d | rs174583 |
| GWAS Ctlg | rs174583 |
| GMAF | 0.3972 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
| GWAS snp | |
|---|---|
| PMID | [PMID 20339536 ]
|
| Trait | Response to statin therapy |
| Title | Genome-wide association of lipid-lowering response to statins in combined study populations |
| Risk Allele | T |
| P-val | 0.000003 |
| Odds Ratio | None None |
[PMID 20395685] Association of fatty acid desaturase gene polymorphisms with blood lipid essential fatty acids and perinatal depression among Canadian women: a pilot study
[PMID 18936223] Genetic variants of the FADS1 FADS2 gene cluster are associated with altered (n-6) and (n-3) essential fatty acids in plasma and erythrocyte phospholipids in women during pregnancy and in breast milk during lactation.
[PMID 20565855] Genetic variation in lipid desaturases and its impact on the development of human disease.
[PMID 22960237] Bivariate genome-wide association study suggests fatty acid desaturase genes and cadherin DCHS2 for variation of both compressive strength index and appendicular lean mass in males
[PMID 29937909] The effect of FADS2 gene rs174583 polymorphism on desaturase activities, fatty acid profile, insulin resistance, biochemical indices, and incidence of type 2 diabetes.
