rs1746048
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 1.3 | 1.03 increased risk for coronary heart disease |
| (C;T) | 1.8 | 0.94 decreased risk for coronary heart disease |
| (T;T) | 2 | 0.85 decreased risk for coronary heart disease |
| Reference | GRCh38 38.1/142 |
| Chromosome | 10 |
| Position | 44280376 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs1746048 |
| dbSNP (classic) | rs1746048 |
| ClinGen | rs1746048 |
| ebi | rs1746048 |
| HLI | rs1746048 |
| Exac | rs1746048 |
| Gnomad | rs1746048 |
| Varsome | rs1746048 |
| LitVar | rs1746048 |
| Map | rs1746048 |
| PheGenI | rs1746048 |
| Biobank | rs1746048 |
| 1000 genomes | rs1746048 |
| hgdp | rs1746048 |
| ensembl | rs1746048 |
| geneview | rs1746048 |
| scholar | rs1746048 |
| rs1746048 | |
| pharmgkb | rs1746048 |
| gwascentral | rs1746048 |
| openSNP | rs1746048 |
| 23andMe | rs1746048 |
| SNPshot | rs1746048 |
| SNPdbe | rs1746048 |
| MSV3d | rs1746048 |
| GWAS Ctlg | rs1746048 |
| GMAF | 0.2833 |
| Max Magnitude | 2 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
23andMe blog coronary artery disease and heart attack
SNP Risk Version Effect
- rs646776 T 1.19
- rs17465637 C 1.14
- rs1746048 C 1.17
- rs6725887 C 1.17
- rs11206510 T 1.15
- rs3184504 T 1.13
- rs2306374 C 1.15
- rs3782886 C 1.44
| GWAS snp | |
|---|---|
| PMID | [PMID 19198609 ]
|
| Trait | Myocardial infarction (early onset) |
| Title | Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants |
| Risk Allele | C |
| P-val | 7E-9 |
| Odds Ratio | 1.17 [1.11-1.24] |
| GWAS snp | |
|---|---|
| PMID | [PMID 21378990]
|
| Trait | |
| Title | Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease |
| Risk Allele | C |
| P-val | 3E-10 |
| Odds Ratio | 1.0900 [1.07-1.13] |
[PMID 21415067] The novel atherosclerosis locus at 10q11 regulates plasma CXCL12 levels
[PMID 19956433] Genetics of coronary artery disease: focus on genome-wide association studies.
[PMID 20835900] Genetics of diabetes complications.
[PMID 23531450] Relationship between Chemokine (C-X-C motif) ligand 12 gene variant (rs1746048) and coronary heart disease: Case-control study and meta-analysis
[PMID 23666823] Genetic variants on chromosome 10q11.21 are associated with ischemic stroke in the northern Chinese Han population.
[PMID 25804320] Association Between Coronary Artery Disease Genetic Variants and Subclinical Atherosclerosis: an Association Study and Meta-analysis
[PMID 26324845] Association of chemokine CXC ligand 12 gene polymorphism (rs1746048) with cardiovascular mortality in patients with rheumatoid arthritis: results from the Norfolk Arthritis Register
[PMID 31862910] The CXCL12 SNPs and their haplotypes are associated with serum lipid traits.
