rs17646665

Orientation

plus

Stabilized

plus

Geno	Mag	Summary
(A;A)	0	common/normal
(A;G)	3.9	Moderately reduced risk for Alzheimer's (~0.6x)
(G;G)	4.2	Reduced risk for Alzheimer's (~0.33x?)

Reference

GRCh38.p2 38.2/147

Chromosome

1

Position

109369429

Gene

SORT1

is a	snp
is	mentioned by
dbSNP	rs17646665
dbSNP (classic)	rs17646665
ClinGen	rs17646665
ebi	rs17646665
HLI	rs17646665
Exac	rs17646665
Gnomad	rs17646665
Varsome	rs17646665
LitVar	rs17646665
Map	rs17646665
PheGenI	rs17646665
Biobank	rs17646665
1000 genomes	rs17646665
hgdp	rs17646665
ensembl	rs17646665
geneview	rs17646665
scholar	rs17646665
google	rs17646665
pharmgkb	rs17646665
gwascentral	rs17646665
openSNP	rs17646665
23andMe	rs17646665
SNPshot	rs17646665
SNPdbe	rs17646665
MSV3d	rs17646665
GWAS Ctlg	rs17646665

Max Magnitude

4.2

?	(A;A) (A;G) (G;G)	28

[PMID 27392867] A Genetic Variant of the Sortilin 1 Gene is Associated with Reduced Risk of Alzheimer's Disease. Minor Allele (G) associated with reduced risk (OR 0.6x, CI: 0.4-0.8) for Alzheimer's Disease; it is possible that the reported association could be restricted to a Swedish/Scandinavian population.