rs1780329
From SNPedia
| Orientation | minus |
| Stabilized | minus |
| Make rs1780329(G;G) |
| Make rs1780329(G;T) |
| Make rs1780329(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 1 |
| Position | 21576457 |
| Gene | ALPL |
| is a | snp |
| is | mentioned by |
| dbSNP | rs1780329 |
| dbSNP (classic) | rs1780329 |
| ClinGen | rs1780329 |
| ebi | rs1780329 |
| HLI | rs1780329 |
| Exac | rs1780329 |
| Gnomad | rs1780329 |
| Varsome | rs1780329 |
| LitVar | rs1780329 |
| Map | rs1780329 |
| PheGenI | rs1780329 |
| Biobank | rs1780329 |
| 1000 genomes | rs1780329 |
| hgdp | rs1780329 |
| ensembl | rs1780329 |
| geneview | rs1780329 |
| scholar | rs1780329 |
| rs1780329 | |
| pharmgkb | rs1780329 |
| gwascentral | rs1780329 |
| openSNP | rs1780329 |
| 23andMe | rs1780329 |
| SNPshot | rs1780329 |
| SNPdbe | rs1780329 |
| MSV3d | rs1780329 |
| GWAS Ctlg | rs1780329 |
| GMAF | 0.3159 |
| Max Magnitude | 0 |
| ? | (G;G) (G;T) (T;T) | 28 |
|---|---|---|
|
| ||
[PMID 17195227] A study of 201 Canadian ankylosing spondylitis families concluded the ALPL (TNAP) haplotype G-G-T for SNPs rs3767155-rs3738099-rs1780329, respectively, is significantly associated with the disease but only in men.
[PMID 18769922] A study of 353 Chinese ankylosing spondylitis patients found no significant difference in allele, genotype or haplotype frequencies for this SNP in either case-control or family-based association studies, which indicated that the TNAP (also known as ALPL) gene is unlikely to play a major role in the susceptibility to ankylosing spondylitis in the Chinese Han population.
