rs1799978
| Orientation | minus |
| Stabilized | minus |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | 0 | common in clinvar |
| Make rs1799978(A;G) |
| Make rs1799978(G;G) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 11 |
| Position | 113475629 |
| Gene | DRD2, LOC105369501 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs1799978 |
| dbSNP (classic) | rs1799978 |
| ClinGen | rs1799978 |
| ebi | rs1799978 |
| HLI | rs1799978 |
| Exac | rs1799978 |
| Gnomad | rs1799978 |
| Varsome | rs1799978 |
| LitVar | rs1799978 |
| Map | rs1799978 |
| PheGenI | rs1799978 |
| Biobank | rs1799978 |
| 1000 genomes | rs1799978 |
| hgdp | rs1799978 |
| ensembl | rs1799978 |
| geneview | rs1799978 |
| scholar | rs1799978 |
| rs1799978 | |
| pharmgkb | rs1799978 |
| gwascentral | rs1799978 |
| openSNP | rs1799978 |
| 23andMe | rs1799978 |
| SNPshot | rs1799978 |
| SNPdbe | rs1799978 |
| MSV3d | rs1799978 |
| GWAS Ctlg | rs1799978 |
| GMAF | 0.1051 |
| Max Magnitude | 0 |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
[PMID 19373123] Genetic variants altering dopamine D2 receptor expression or function modulate the risk of opiate addiction and the dosage requirements of methadone substitution
[PMID 19512960] Genetic diagnostics of functional variants of the human dopamine D2 receptor gene
[PMID 18305461
] Association between ADORA2A and DRD2 polymorphisms and caffeine-induced anxiety.
[PMID 18330705] Physiogenomic analysis of localized FMRI brain activity in schizophrenia.
[PMID 19968402] Evaluation of genetic variability in the dopamine receptor D2 in relation to behavioral inhibition and impulsivity/sensation seeking: an exploratory study with d-amphetamine in healthy participants.
[PMID 21162693] Pharmacogenetics and antipsychotics: therapeutic efficacy and side effects prediction.
[PMID 23828101] Impulsivity and genetic variants in DRD2 and ANKK1 moderate longitudinal associations between sleep problems and overweight from ages 5 to 11.
| ClinVar | |
|---|---|
| Risk | rs1799978(G;G) |
| Alt | rs1799978(G;G) |
| Reference | Rs1799978(A;A) |
| Significance | Drug-response |
| Disease | risperidone response - Efficacy |
| Variation | info |
| Gene | DRD2 |
| CLNDBN | risperidone response - Efficacy |
| Reversed | 1 |
| HGVS | NC_000011.9:g.113346351T>C |
| CLNSRC | PharmGKB Clinical Annotation |
| CLNACC | RCV000211152.1, |
