rs1801159
| Orientation | minus |
| Stabilized | minus |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | 0 | common in clinvar |
| (T;T) | 0 |
| Make rs1801159(A;G) |
| Make rs1801159(G;G) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 1 |
| Position | 97515839 |
| Gene | DPYD |
| is a | snp |
| is | mentioned by |
| dbSNP | rs1801159 |
| dbSNP (classic) | rs1801159 |
| ClinGen | rs1801159 |
| ebi | rs1801159 |
| HLI | rs1801159 |
| Exac | rs1801159 |
| Gnomad | rs1801159 |
| Varsome | rs1801159 |
| LitVar | rs1801159 |
| Map | rs1801159 |
| PheGenI | rs1801159 |
| Biobank | rs1801159 |
| 1000 genomes | rs1801159 |
| hgdp | rs1801159 |
| ensembl | rs1801159 |
| geneview | rs1801159 |
| scholar | rs1801159 |
| rs1801159 | |
| pharmgkb | rs1801159 |
| gwascentral | rs1801159 |
| openSNP | rs1801159 |
| 23andMe | rs1801159 |
| SNPshot | rs1801159 |
| SNPdbe | rs1801159 |
| MSV3d | rs1801159 |
| GWAS Ctlg | rs1801159 |
| GMAF | 0.2048 |
| Max Magnitude | 0 |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
[PMID 19104657
] Strong association of a common dihydropyrimidine dehydrogenase gene polymorphism with fluoropyrimidine-related toxicity in cancer patients.
[PMID 21362212] [Detection of single nucleotide polymorphisms of mthfr and dpyd genes in leukemia cell lines K562 and K562/A02].
[PMID 25027354] [Thymidine phosphorylase gene variant, platelet counts and survival in gastrointestinal cancer patients treated by fluoropyrimidines].
[PMID 23988873] [Clinical Pharmacogenetics Implementation Consortium guidelines for dihydropyrimidine dehydrogenase genotype and fluoropyrimidine dosing].
[PMID 23942539] [Potential of dihydropyrimidine dehydrogenase genotypes in personalizing 5-fluorouracil therapy among colorectal cancer patients].
| ClinVar | |
|---|---|
| Risk | rs1801159(G;G) |
| Alt | rs1801159(G;G) |
| Reference | Rs1801159(A;A) |
| Significance | Probable-non-pathogenic |
| Disease | not provided not specified Dihydropyrimidine dehydrogenase deficiency |
| Variation | info |
| Gene | DPYD |
| CLNDBN | not provided not specified Dihydropyrimidine dehydrogenase deficiency |
| Reversed | 1 |
| HGVS | NC_000001.10:g.97981395T>C |
| CLNSRC | UniProtKB (protein) |
| CLNACC | RCV000086475.1, RCV000174446.2, RCV000389596.1, |
[PMID 29372689] DPYD genotype and haplotype analysis and colorectal cancer susceptibility in a case-control study from Slovakia.
