rs1801177
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (G;G) | 0 | common in clinvar |
| Make rs1801177(A;A) |
| Make rs1801177(A;G) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 8 |
| Position | 19948197 |
| Gene | LPL |
| is a | snp |
| is | mentioned by |
| dbSNP | rs1801177 |
| dbSNP (classic) | rs1801177 |
| ClinGen | rs1801177 |
| ebi | rs1801177 |
| HLI | rs1801177 |
| Exac | rs1801177 |
| Gnomad | rs1801177 |
| Varsome | rs1801177 |
| LitVar | rs1801177 |
| Map | rs1801177 |
| PheGenI | rs1801177 |
| Biobank | rs1801177 |
| 1000 genomes | rs1801177 |
| hgdp | rs1801177 |
| ensembl | rs1801177 |
| geneview | rs1801177 |
| scholar | rs1801177 |
| rs1801177 | |
| pharmgkb | rs1801177 |
| gwascentral | rs1801177 |
| openSNP | rs1801177 |
| 23andMe | rs1801177 |
| SNPshot | rs1801177 |
| SNPdbe | rs1801177 |
| MSV3d | rs1801177 |
| GWAS Ctlg | rs1801177 |
| GMAF | 0.01423 |
| Max Magnitude | 0 |
[PMID 20429872
] Additive effects of LPL, APOA5 and APOE variant combinations on triglyceride levels and hypertriglyceridemia: results of the ICARIA genetic sub-study
| ClinVar | |
|---|---|
| Risk | rs1801177(A;A) rs1801177(C;C) |
| Alt | rs1801177(A;A) rs1801177(C;C) |
| Reference | Rs1801177(G;G) |
| Significance | Other |
| Disease | Hyperlipidemia Coronary heart disease Hyperlipoproteinemia not specified |
| Variation | info |
| Gene | LPL |
| CLNDBN | Hyperlipidemia, familial combined Coronary heart disease Hyperlipoproteinemia, type I not specified |
| Reversed | 0 |
| HGVS | NC_000008.10:g.19805708G>A |
| CLNSRC | OMIM Allelic Variant UniProtKB (protein) |
| CLNACC | RCV000001617.2, RCV000157298.1, RCV000352575.1, RCV000454647.1, |
[PMID 17357073] Genetic analysis of 103 candidate genes for coronary artery disease and associated phenotypes in a founder population reveals a new association between endothelin-1 and high-density lipoprotein cholesterol.
[PMID 18513389] New application of intelligent agents in sporadic amyotrophic lateral sclerosis identifies unexpected specific genetic background.
[PMID 18922999] Seven lipoprotein lipase gene polymorphisms, lipid fractions, and coronary disease: a HuGE association review and meta-analysis.
[PMID 19041386] Genetic-epidemiological evidence on genes associated with HDL cholesterol levels: a systematic in-depth review.
[PMID 19131662] A meta-analysis of candidate gene polymorphisms and ischemic stroke in 6 study populations: association of lymphotoxin-alpha in nonhypertensive patients.
[PMID 20406163] Fenofibrate and metabolic syndrome.
[PMID 21146168] LPL polymorphism (D9N) predicts cardiovascular disease risk directly and through interaction with CETP polymorphism (TaqIB) in women with high HDL cholesterol and CRP.
[PMID 22236405] LPL gene variants affect apoC-III response to combination therapy of statins and fenofibric acid in a randomized clinical trial of individuals with mixed dyslipidemia.
[PMID 28143480] Common variants in the genes of triglyceride and HDL-C metabolism lack association with coronary artery disease in the Pakistani subjects.
