rs1801426

plus

Geno	Mag	Summary
(A;A)	0	common in complete genomics
(A;G)	1	Benign or at worst a very minor risk factor
(G;G)	2

Reference

GRCh38 38.1/141

Chromosome

13

Position

32398747

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs1801426
dbSNP (classic)	rs1801426
ClinGen	rs1801426
ebi	rs1801426
HLI	rs1801426
Exac	rs1801426
Gnomad	rs1801426
Varsome	rs1801426
LitVar	rs1801426
Map	rs1801426
PheGenI	rs1801426
Biobank	rs1801426
1000 genomes	rs1801426
hgdp	rs1801426
ensembl	rs1801426
geneview	rs1801426
scholar	rs1801426
google	rs1801426
pharmgkb	rs1801426
gwascentral	rs1801426
openSNP	rs1801426
23andMe	rs1801426
SNPshot	rs1801426
SNPdbe	rs1801426
MSV3d	rs1801426
GWAS Ctlg	rs1801426

GMAF

0.04362

Max Magnitude

2

?

(A;A) (A;G) (G;G)

28

This SNP, a variant in the BRCA2 gene, is 1 of 25 SNPs reported to represent independently minor, but cumulatively significant, increased risk for breast cancer. [PMID 17341484]

For details of all 25 SNPs in this group, along with the two methods used to calculate overall risk estimates for breast cancer, refer to the SNPedia breast cancer entry.

For this particular SNP, the risk (minor) allele is (G).

23andMe name: i5009256

ClinVar
Risk	Rs1801426(G;G)
Alt	Rs1801426(G;G)
Reference	Rs1801426(A;A)
Significance	Other
Disease	not provided Breast-ovarian cancer not specified Hereditary cancer-predisposing syndrome Hereditary breast and ovarian cancer syndrome Fanconi anemia Neoplasm of breast Familial cancer of breast
Variation	info
Gene	BRCA2
CLNDBN	not provided Breast-ovarian cancer, familial 2 not specified Hereditary cancer-predisposing syndrome Hereditary breast and ovarian cancer syndrome Fanconi anemia Neoplasm of breast Familial cancer of breast
Reversed	0
HGVS	NC_000013.10:g.32972884A>G
CLNSRC	HGMD
CLNACC	RCV000034426.4, RCV000112853.5, RCV000120373.7, RCV000130982.4, RCV000267039.2, RCV000361728.1, RCV000414645.1, RCV000460200.1,