rs1805034

plus

Geno	Mag	Summary
(C;C)	0	common in clinvar

Reference

GRCh38 38.1/141

Chromosome

18

Position

62360008

Gene

0.3953

0

(C;C) (C;T) (T;T)

28

[PMID 20231205] Genetic Variations in Genes Encoding RANK, RANKL, and OPG in Rheumatoid Arthritis: A Case-Control Study

[PMID 20564239] Genetic variation in the TNFRSF11A gene encoding RANK is associated with susceptibility to Paget's disease of bone

[PMID 21760914 ] Pathway-based association analyses identified TRAIL pathway for osteoporotic fractures

[PMID 22023082 ] Association analyses suggest the effects of RANK and RANKL on age at menarche in Chinese women.

[PMID 23369128 ] Genetic polymorphism of the OPG gene associated with breast cancer

[PMID 26451891] RANK rs1805034 T>C Polymorphism Is Associated with Susceptibility to Gastric Cardia Adenocarcinoma in a Chinese Population

ClinVar
Risk	rs1805034(T;T)
Alt	rs1805034(T;T)
Reference	Rs1805034(C;C)
Significance	Probable-non-pathogenic
Disease	not specified Osteopetrosis Paget disease of bone
Variation	info
Gene	TNFRSF11A
CLNDBN	not specified Osteopetrosis Paget disease of bone
Reversed	0
HGVS	NC_000018.9:g.60027241C>T
CLNSRC
CLNACC	RCV000252411.1, RCV000280881.1, RCV000338163.1,

[PMID 28244588] Investigation of OPG/RANK/RANKL Genes as a Genetic Marker for Cardiac abnormalities in Thalassemia Major Patients.

[PMID 31658533] [Association between TNFRSF11A and TNFRSF11B gene polymorphisms and the outcome of hepatitis C virus infection].