rs1805126

Orientation

minus

Stabilized

minus

Geno	Mag	Summary
(T;T)	0	common in clinvar

Make rs1805126(C;C)

Make rs1805126(C;T)

Reference

GRCh38 38.1/141

Chromosome

3

Position

38550915

Gene

SCN5A

is a	snp
is	mentioned by
dbSNP	rs1805126
dbSNP (classic)	rs1805126
ClinGen	rs1805126
ebi	rs1805126
HLI	rs1805126
Exac	rs1805126
Gnomad	rs1805126
Varsome	rs1805126
LitVar	rs1805126
Map	rs1805126
PheGenI	rs1805126
Biobank	rs1805126
1000 genomes	rs1805126
hgdp	rs1805126
ensembl	rs1805126
geneview	rs1805126
scholar	rs1805126
google	rs1805126
pharmgkb	rs1805126
gwascentral	rs1805126
openSNP	rs1805126
23andMe	rs1805126
SNPshot	rs1805126
SNPdbe	rs1805126
MSV3d	rs1805126
GWAS Ctlg	rs1805126

GMAF

0.4936

Max Magnitude

0

?	(C;C) (C;T) (T;T)	28

GWAS snp
PMID	[PMID 23463857]
Trait	Electrocardiographic conduction measures
Title	Genome- and phenome-wide analyses of cardiac conduction identifies markers of arrhythmia risk.
Risk Allele	A
P-val	3E-20
Odds Ratio	.66 [NR] msec decrease

[PMID 17534376] Confirmation of associations between ion channel gene SNPs and QTc interval duration in healthy subjects.

[PMID 18368697] SCN5A variants in Japanese patients with left ventricular noncompaction and arrhythmia.

ClinVar
Risk	rs1805126(C;C)
Alt	rs1805126(C;C)
Reference	Rs1805126(T;T)
Significance	Probable-non-pathogenic
Disease	not specified Cardiovascular phenotype Brugada syndrome Romano-Ward syndrome Long QT syndrome Dilated Cardiomyopathy Paroxysmal familial ventricular fibrillation Sick sinus syndrome Progressive familial heart block
Variation	info
Gene	SCN5A
CLNDBN	not specified Cardiovascular phenotype Brugada syndrome Romano-Ward syndrome Long QT syndrome Dilated Cardiomyopathy, Dominant Paroxysmal familial ventricular fibrillation Sick sinus syndrome Progressive familial heart block
Reversed	1
HGVS	NC_000003.11:g.38592406A>G
CLNSRC	ClinVar GeneDx
CLNACC	RCV000041627.5, RCV000243623.1, RCV000286827.1, RCV000302171.1, RCV000335948.1, RCV000341786.1, RCV000347752.1, RCV000371957.1, RCV000390614.1,