rs1805762
From SNPedia
| Orientation | minus |
| Stabilized | minus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | >1.23x risk for hypertension | |
| (C;G) | 1.23x risk for hypertension | |
| (G;G) | average |
| Reference | GRCh38 38.1/141 |
| Chromosome | 12 |
| Position | 8945306 |
| Gene | M6PR |
| is a | snp |
| is | mentioned by |
| dbSNP | rs1805762 |
| dbSNP (classic) | rs1805762 |
| ClinGen | rs1805762 |
| ebi | rs1805762 |
| HLI | rs1805762 |
| Exac | rs1805762 |
| Gnomad | rs1805762 |
| Varsome | rs1805762 |
| LitVar | rs1805762 |
| Map | rs1805762 |
| PheGenI | rs1805762 |
| Biobank | rs1805762 |
| 1000 genomes | rs1805762 |
| hgdp | rs1805762 |
| ensembl | rs1805762 |
| geneview | rs1805762 |
| scholar | rs1805762 |
| rs1805762 | |
| pharmgkb | rs1805762 |
| gwascentral | rs1805762 |
| openSNP | rs1805762 |
| 23andMe | rs1805762 |
| SNPshot | rs1805762 |
| SNPdbe | rs1805762 |
| MSV3d | rs1805762 |
| GWAS Ctlg | rs1805762 |
| GMAF | 0.09963 |
| Max Magnitude | 0 |
| ? | (C;C) (C;G) (G;G) | 28 |
|---|---|---|
|
| ||
rs1805762, a SNP in the M6PR gene, was associated with risk for hypertension in a study involving 1,500+ Japanese patients. The odds ratio associated with the risk allele, in dbSNP orientation, rs1805762(G), which is also the most common allele, is 1.23 (CI: 1.10 - 1.37, p = 0.0003). [PMID 18003638]
A SNP in close linkage, rs1805740, has also been reported in association with hypertension risk in the large 2007 study reported by the Wellcome Trust Consortium. [PMID 17554300
]
