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High blood pressure

From SNPedia
(Redirected from Hypertension)

The Wikipedia article on high blood pressure gives a general introduction. "High blood pressure" is the common term for the medically accurate term hypertension.

Genetic variation associated with high blood pressure can be divided into

SNPs that may predispose individuals to high blood pressure include:

  • [PMID 16565233] A -318 C>G single-nucleotide polymorphism in the GNAI2 gene promoter region is associated with high blood pressure in Caucasians from Italy. Note: this SNP does not appear to have a corresponding entry in dbSNP.
  • rs1799983 is a SNP in the NOS3 gene that reflects a 2x higher risk of developing hypertension during pregnancy (pre-eclampsia). [PMID 11745998] This is true for carriers of one or two risk alleles.

SNPs possibly affecting beta blocker therapy for hypertension include: