rs1843809
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (G;G) | 1.5 | slightly decreased risk for ADHD |
| (T;T) | 1 | Most common genotype worldwide |
| Make rs1843809(G;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 12 |
| Position | 71954918 |
| Gene | TPH2 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs1843809 |
| dbSNP (classic) | rs1843809 |
| ClinGen | rs1843809 |
| ebi | rs1843809 |
| HLI | rs1843809 |
| Exac | rs1843809 |
| Gnomad | rs1843809 |
| Varsome | rs1843809 |
| LitVar | rs1843809 |
| Map | rs1843809 |
| PheGenI | rs1843809 |
| Biobank | rs1843809 |
| 1000 genomes | rs1843809 |
| hgdp | rs1843809 |
| ensembl | rs1843809 |
| geneview | rs1843809 |
| scholar | rs1843809 |
| rs1843809 | |
| pharmgkb | rs1843809 |
| gwascentral | rs1843809 |
| openSNP | rs1843809 |
| 23andMe | rs1843809 |
| SNPshot | rs1843809 |
| SNPdbe | rs1843809 |
| MSV3d | rs1843809 |
| GWAS Ctlg | rs1843809 |
| GMAF | 0.1947 |
| Max Magnitude | 1.5 |
| ? | (G;G) (G;T) (T;T) | 28 |
|---|---|---|
|
| ||
[PMID 19679166] TPH2 polymorphisms may modify clinical picture in treatment-resistant depression
[PMID 15940290] Tryptophan hydroxylase 2 (TPH2) gene variants associated with ADHD.
[PMID 16380908
] Preferential transmission of paternal alleles at risk genes in attention-deficit/hyperactivity disorder.
[PMID 16894395] The analysis of 51 genes in DSM-IV combined type attention deficit hyperactivity disorder: association signals in DRD4, DAT1 and 16 other genes.
[PMID 17123708] No association between TPH2 gene polymorphisms and ADHD in a UK sample.
[PMID 19742166] Epistasis between IL1A, IL1B, TNF, HTR2A, 5-HTTLPR and TPH2 variations does not impact alcohol dependence disorder features.
[PMID 20446882] Do candidate genes discriminate patients with an autism spectrum disorder from those with attention deficit/hyperactivity disorder and is there an effect of lifetime substance use disorders?
[PMID 21172166] Pharmacogenetics of antidepressant response.
[PMID 21182896] TPH2 polymorphisms and alcohol-related suicide.
[PMID 23461725] Association between TPH2 gene polymorphisms and attention deficit hyperactivity disorder in Korean children.
[PMID 26232682] Genetic variability in tryptophan hydroxylase 2 gene in alcohol dependence and alcohol-related psychopathological symptoms
