rs1870377
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (T;T) | 0 | common in clinvar |
| Make rs1870377(A;A) |
| Make rs1870377(A;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 4 |
| Position | 55106807 |
| Gene | KDR |
| is a | snp |
| is | mentioned by |
| dbSNP | rs1870377 |
| dbSNP (classic) | rs1870377 |
| ClinGen | rs1870377 |
| ebi | rs1870377 |
| HLI | rs1870377 |
| Exac | rs1870377 |
| Gnomad | rs1870377 |
| Varsome | rs1870377 |
| LitVar | rs1870377 |
| Map | rs1870377 |
| PheGenI | rs1870377 |
| Biobank | rs1870377 |
| 1000 genomes | rs1870377 |
| hgdp | rs1870377 |
| ensembl | rs1870377 |
| geneview | rs1870377 |
| scholar | rs1870377 |
| rs1870377 | |
| pharmgkb | rs1870377 |
| gwascentral | rs1870377 |
| openSNP | rs1870377 |
| 23andMe | rs1870377 |
| SNPshot | rs1870377 |
| SNPdbe | rs1870377 |
| MSV3d | rs1870377 |
| GWAS Ctlg | rs1870377 |
| GMAF | 0.2346 |
| Max Magnitude | 0 |
| ? | (A;A) (A;T) (T;T) | 28 |
|---|---|---|
|
| ||
[PMID 19875757] Clinical relevance of vascular endothelial growth factor (VEGFA) and VEGF receptor (VEGFR2) gene polymorphism on the treatment outcome following imatinib therapy
[PMID 22015057] Single nucleotide polymorphism associations with response and toxic effects in patients with advanced renal-cell carcinoma treated with first-line sunitinib: a multicentre, observational, prospective study
[PMID 22129133
] VEGFA and VEGFR2 genetic polymorphisms and survival in patients with diffuse large B cell lymphoma
[PMID 22507619] Association and interaction between dietary pattern and VEGF receptor-2 (VEGFR2) gene polymorphisms on blood lipids in Chinese Malaysian and Japanese adults
[PMID 18194558] A hierarchical and modular approach to the discovery of robust associations in genome-wide association studies from pooled DNA samples.
[PMID 20019880] Polymorphisms in the VEGFA and VEGFR-2 genes and neovascular age-related macular degeneration.
[PMID 20215856] Genetic association of angiogenesis- and hypoxia-related gene polymorphisms with osteonecrosis of the femoral head.
[PMID 20389299] Pazopanib-induced hyperbilirubinemia is associated with Gilbert's syndrome UGT1A1 polymorphism.
[PMID 21257617] Association of polymorphisms/haplotypes of the genes encoding vascular endothelial growth factor and its KDR receptor with recurrent pregnancy loss.
[PMID 23111153] Implication of VEGFR2 in systemic lupus erythematosus: a combined genetic and structural biological approach
[PMID 23566851] Association study between of Tie2/angiopoietin-2 and VEGF/KDR pathway gene polymorphisms and vascular malformations
[PMID 25123269] Genetic variants in the KDR gene is associated with the prognosis of transarterial chemoembolization treated hepatocellular carcinoma
| ClinVar | |
|---|---|
| Risk | rs1870377(A;A) |
| Alt | rs1870377(A;A) |
| Reference | Rs1870377(T;T) |
| Significance | Untested |
| Disease | not specified |
| Variation | info |
| Gene | KDR |
| CLNDBN | not specified |
| Reversed | 0 |
| HGVS | NC_000004.11:g.55972974T>A |
| CLNSRC | UniProtKB (protein) |
| CLNACC | RCV000121293.1, |
[PMID 26081139] Genetic Variations of Kinase Inserts Domain Receptor (KDR) Gene Are Associated with the Risk of Astrocytomas
[PMID 26254278] Impact of VEGF, VEGFR, PDGFR, HIF and ERCC1 gene polymorphisms on thymic malignancies outcome after thymectomy
[PMID 25182707] The relationship of kinase insert domain receptor gene polymorphisms and clinical outcome in advanced hepatocellular carcinoma patients treated with sorafenib
[PMID 27141535] Association of kinase insert domain-containing receptor (KDR) gene polymorphism/ haplotypes with recurrent spontaneous abortion and genetic structure.
[PMID 29054076] Genetic polymorphisms in angiogenesis-related genes are associated with worse progression-free survival of patients with advanced gastrointestinal stromal tumours treated with imatinib.
[PMID 32997825] VEGFR2 and VEGFA polymorphism are not associated with an inferior prognosis in Caucasian patients with aggressive B-cell lymphoma.
[PMID 33238394] VEGF-Related Germinal Polymorphisms May Identify a Subgroup of Breast Cancer Patients with Favorable Outcome under Bevacizumab-Based Therapy-A Message from COMET, a French Unicancer Multicentric Study.
