rs2069832
| Orientation | plus |
| Stabilized | plus |
| Make rs2069832(A;A) |
| Make rs2069832(A;G) |
| Make rs2069832(G;G) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 7 |
| Position | 22727814 |
| Gene | IL6, LOC541472 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs2069832 |
| dbSNP (classic) | rs2069832 |
| ClinGen | rs2069832 |
| ebi | rs2069832 |
| HLI | rs2069832 |
| Exac | rs2069832 |
| Gnomad | rs2069832 |
| Varsome | rs2069832 |
| LitVar | rs2069832 |
| Map | rs2069832 |
| PheGenI | rs2069832 |
| Biobank | rs2069832 |
| 1000 genomes | rs2069832 |
| hgdp | rs2069832 |
| ensembl | rs2069832 |
| geneview | rs2069832 |
| scholar | rs2069832 |
| rs2069832 | |
| pharmgkb | rs2069832 |
| gwascentral | rs2069832 |
| openSNP | rs2069832 |
| 23andMe | rs2069832 |
| SNPshot | rs2069832 |
| SNPdbe | rs2069832 |
| MSV3d | rs2069832 |
| GWAS Ctlg | rs2069832 |
| GMAF | 0.1837 |
| Max Magnitude | 0 |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
[PMID 18727828
] 7thspace stroke rs2069832(C) (African-American frequency = 92%) significantly associated with stroke only among African-Americans (age-adjusted: OR =2.2, 95% CI=1.0-5.0, p=0.049; risk factor adjusted: OR =2.5, 95% CI=1.0-6.5, p=0.05).
[PMID 22459738] Genetic and Immunological Evidence Implicates Interleukin 6 as a Susceptibility Gene for Leprosy Type 2 Reaction
[PMID 17594514] Active and passive smoking, IL6, ESR1, and breast cancer risk.
[PMID 17694420] IL6 genotypes and colon and rectal cancer.
[PMID 18239642] Modifying effects of IL-6 polymorphisms on body size-associated breast cancer risk.
[PMID 18420533] The effect of IL6-174C/G polymorphism on postprandial triglyceride metabolism in the GOLDN studyboxs.
[PMID 18496509] An IL-6 haplotype on human chromosome 7p21 confers risk for impaired renal function in type 2 diabetic patients.
[PMID 19035456] Adipokine genes and prostate cancer risk.
[PMID 19267250] C-reactive protein, interleukin-6, and prostate cancer risk in men aged 65 years and older.
[PMID 19359268] Associations of IL6 polymorphisms with lung function decline and COPD.
[PMID 19750100] Modification of the interleukin-6 response to air pollution by interleukin-6 and fibrinogen polymorphisms.
[PMID 20011102] Fine-scale variation and genetic determinants of alternative splicing across individuals.
[PMID 23251429] Inflammation and immune-related candidate gene associations with acute lung injury susceptibility and severity: a validation study.
