rs2069912
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | sepsis risk in East Asians | |
| (C;T) | sepsis risk in East Asians | |
| (T;T) | 0 | normal |
| Reference | GRCh38 38.1/141 |
| Chromosome | 2 |
| Position | 127420615 |
| Gene | PROC |
| is a | snp |
| is | mentioned by |
| dbSNP | rs2069912 |
| dbSNP (classic) | rs2069912 |
| ClinGen | rs2069912 |
| ebi | rs2069912 |
| HLI | rs2069912 |
| Exac | rs2069912 |
| Gnomad | rs2069912 |
| Varsome | rs2069912 |
| LitVar | rs2069912 |
| Map | rs2069912 |
| PheGenI | rs2069912 |
| Biobank | rs2069912 |
| 1000 genomes | rs2069912 |
| hgdp | rs2069912 |
| ensembl | rs2069912 |
| geneview | rs2069912 |
| scholar | rs2069912 |
| rs2069912 | |
| pharmgkb | rs2069912 |
| gwascentral | rs2069912 |
| openSNP | rs2069912 |
| 23andMe | rs2069912 |
| SNPshot | rs2069912 |
| SNPdbe | rs2069912 |
| MSV3d | rs2069912 |
| GWAS Ctlg | rs2069912 |
| GMAF | 0.3159 |
| Max Magnitude | 0 |
The rs2069912(C) allele is associated with severe sepsis and thus increased risk of death and organ dysfunction based on a study of 100 North American East Asians. The original report of this association was (also) in Chinese patients.[PMID 18496716]
[PMID 19941661
] A MIF haplotype is associated with the outcome of patients with severe sepsis: a case control study.
