[PMID 17713557] Visceral leishmaniasis (VL) caused by Leishmania chagasi is endemic to northeast Brazil. A positive delayed-type hypersensitivity skin test response (DTH+) is a marker for acquired resistance to disease. the DTH- phenotype was associated with SNP rs2070874 at IL4 (OR 3.14; P=0.006; 95% CI=1.38-7.14), and SNP rs30740 between LECT2 and TGFBI (OR 3.00; P=0.042; 95% CI=1.04-8.65)
[PMID 19254294] Contribution of functional variation in the IL13 gene to allergy, hay fever and asthma in the NSHD longitudinal 1946 birth cohort.
[PMID 19058298] Promoter polymorphisms of IL2, IL4, and risk of gastric cancer in a high-risk Chinese population
[PMID 20032229] Prediction of functional impairment and remission in rheumatoid arthritis patients by biochemical variables and genetic polymorphisms
[PMID 20332709] Association analysis of polymorphisms in IL-3, IL-4, IL-5, IL-9 and IL-13 with Graves' disease
[PMID 20921925] Effect of single nucleotide polymorphisms within the interleukin-4 promoter on aspirin intolerance in asthmatics and interleukin-4 promoter activity
[PMID 22053598] Association of TGF-beta1, IL-4 and IL-13 gene polymerphisms with asthma in a Chinese population
[PMID 22377791] Association of genetic polymorphisms of interleukins with new-onset diabetes after transplantation in renal transplantation
[PMID 15570643] Epistatic interactions between HLA-DRB1 and interleukin 4, but not interferon-gamma, increase susceptibility to giant cell arteritis.
[PMID 15660293] No evidence of association or interaction between the IL4RA, IL4, and IL13 genes in type 1 diabetes.
[PMID 16449530] Cytokine polymorphisms in the Th1/Th2 pathway and susceptibility to non-Hodgkin lymphoma.
[PMID 17303794] Ethnicity-specific gene-gene interaction between IL-13 and IL-4Ralpha among African Americans with asthma.
[PMID 17327408] Prognostic significance of host immune gene polymorphisms in follicular lymphoma survival.
[PMID 18056382] Analysis of the 5q31 33 locus shows an association between single nucleotide polymorphism variants in the IL-5 gene and symptomatic infection with the human blood fluke, Schistosoma japonicum.
[PMID 18454680] Genetic basis for adverse events after smallpox vaccination.
[PMID 18538381] Clinical and genetic risk factors of self-reported penicillin allergy.
[PMID 18633131] Host immune gene polymorphisms in combination with clinical and demographic factors predict late survival in diffuse large B-cell lymphoma patients in the pre-rituximab era.
[PMID 18676870] Variants in inflammation genes and the risk of biliary tract cancers and stones: a population-based study in China.
[PMID 18781131] Interleukin and interleukin receptor gene polymorphisms and susceptibility to melanoma.
[PMID 19066394] Organochlorine exposure, immune gene variation, and risk of non-Hodgkin lymphoma.
[PMID 19356949] Cytokine SNPs: Comparison of allele frequencies by race and implications for future studies.
[PMID 19468064] Parasites represent a major selective force for interleukin genes and shape the genetic predisposition to autoimmune conditions.
[PMID 19840389] Identification of a haplotype block in the 5q31 cytokine gene cluster associated with the susceptibility to severe malaria.
[PMID 20015396] Innate immunity in ocular Chlamydia trachomatis infection: contribution of IL8 and CSF2 gene variants to risk of trachomatous scarring in Gambians.
[PMID 20525402] Analysis of eight genes modulating interferon gamma and human genetic susceptibility to tuberculosis: a case-control association study.
[PMID 20811626] Genetic variants in inflammation-related genes are associated with radiation-induced toxicity following treatment for non-small cell lung cancer.
[PMID 21320344] Evaluation of genetic susceptibility to childhood allergy and asthma in an African American urban population.
[PMID 21387019] Differences in candidate gene association between European ancestry and African American asthmatic children.
[PMID 21501388] Association between interleukin-4 gene polymorphisms and intracerebral haemorrhage in Korean population.
[PMID 22528336] Association study of interleukin-4 polymorphisms with paranoid schizophrenia in the Polish population: a critical approach.
[PMID 23572437] Three common polymorphisms in the IL-4 gene and cancer risk: A meta-analysis involving 5,392 cases and 6,930 controls
[PMID 23651591] Association of polymorphisms in the interleukin-4 gene with response to hepatitis B vaccine and susceptibility to hepatitis B virus infection: a meta-analysis
[PMID 23654077] IL-4 gene polymorphisms and their association with atopic asthma and allergic rhinitis in Pakistani patients
[PMID 23668806] Association of IL-4 and IL-10 maternal haplotypes with immune responses to P. falciparum in mothers and newborns
[PMID 23924473] Association between the polymorphisms of interleukin-4, the interleukin-4 receptor gene and asthma
[PMID 23964553] Relationship between polymorphisms in IL4 and asthma in Japanese women: the Kyushu Okinawa Maternal and Child Health Study
[PMID 24463336] Association of Interleukin-4 genetic polymorphisms with sporadic Alzheimer's disease in Chinese Han population
[PMID 22573572] Phenotype-genotype profiles in Crohn's disease predicted by genetic markers in autophagy-related genes (GOIA study II).
[PMID 22824342] Association of polymorphisms of cytokine and TLR-2 genes with long-term immunity to hepatitis B in children vaccinated early in life.
[PMID 22884982] Polymorphisms in the IL4 gene, smoking, and rhinoconjunctivitis in Japanese women: the Kyushu Okinawa Maternal and Child Health Study.
[PMID 23459936] Exploring the genetic basis of chronic periodontitis: a genome-wide association study.
[PMID 23663310] Investigating highly replicated asthma genes as candidate genes for allergic rhinitis.
[PMID 25295591] Role of IL-4 Gene Polymorphisms in HBV-Related Hepatocellular Carcinoma in a Chinese Population
[PMID 25768087] An ADAM33 Polymorphism Associates with Progression of Preschool Wheeze into Childhood Asthma: A Prospective Case-Control Study with Replication in a Birth Cohort Study
[PMID 25785117] Associations between polymorphisms in the IL-4 and IL-4 receptor genes and urinary carcinomas: a meta-analysis
[PMID 26681045] Investigation of polymorphisms in anti-inflammatory cytokine genes in hematogenous osteomyelitis.
[PMID 28289589] Polymorphism of the IL13 gene may be associated with Uterine leiomyomas in Slovenian women.
[PMID 30130760] Genes Regulating Immune Response and Amelogenesis Interact in Increasing the Susceptibility to Molar-Incisor Hypomineralization.
[PMID 31264107] Association between interleukin-4 and interleukin-10 single nucleotide polymorphisms and multiple sclerosis among Iraqi patients.