rs2074190
From SNPedia
| Orientation | minus |
| Stabilized | minus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 2.2x risk for AIA | |
| (C;T) | 2.2x risk for AIA | |
| (T;T) | 0 | common |
| Reference | GRCh38 38.1/142 |
| Chromosome | 17 |
| Position | 47733844 |
| Gene | TBX21 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs2074190 |
| dbSNP (classic) | rs2074190 |
| ClinGen | rs2074190 |
| ebi | rs2074190 |
| HLI | rs2074190 |
| Exac | rs2074190 |
| Gnomad | rs2074190 |
| Varsome | rs2074190 |
| LitVar | rs2074190 |
| Map | rs2074190 |
| PheGenI | rs2074190 |
| Biobank | rs2074190 |
| 1000 genomes | rs2074190 |
| hgdp | rs2074190 |
| ensembl | rs2074190 |
| geneview | rs2074190 |
| scholar | rs2074190 |
| rs2074190 | |
| pharmgkb | rs2074190 |
| gwascentral | rs2074190 |
| openSNP | rs2074190 |
| 23andMe | rs2074190 |
| SNPshot | rs2074190 |
| SNPdbe | rs2074190 |
| MSV3d | rs2074190 |
| GWAS Ctlg | rs2074190 |
| GMAF | 0.2401 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
rs2074190(G;G) and rs2074190(A;G) genotypes for the TBX21 gene are calculated to be at 2.19 fold higher risk (CI: 1.27-3.77) for aspirin-induced asthma (AIA) compared to rs2074190(A;A) homozygotes, based on a study of 72 patients vs 640 controls in a study of a Japanese population. [PMID 15806396]
Note that in this population, but perhaps not others, linkage disequilibrium exists between this SNP located in the first exon, rs2074190, and a SNP located upstream of the gene, rs4794067, with a predictive accuracy of 92%.
