TBX21
From SNPedia
| is a | gene |
| is | mentioned by |
| Full name | T-box 21 |
| EntrezGene | 30009 |
| PheGenI | 30009 |
| VariationViewer | 30009 |
| ClinVar | TBX21 |
| GeneCards | TBX21 |
| dbSNP | 30009 |
| Diseases | TBX21 |
| SADR | 30009 |
| HugeNav | 30009 |
| wikipedia | TBX21 |
| TBX21 | |
| gopubmed | TBX21 |
| EVS | TBX21 |
| HEFalMp | TBX21 |
| MyGene2 | TBX21 |
| 23andMe | TBX21 |
| UniProt | Q9UL17 |
| Ensembl | ENSG00000073861 |
| OMIM | 604895 |
| # SNPs | 8 |
| Max Magnitude | Chromosome position | Summary | |
|---|---|---|---|
| rs11650354 | 2 | 47,744,726 | |
| rs16947078 | 0 | 47,748,134 | |
| rs17244587 | 0 | 47,745,669 | |
| rs17250932 | 2 | 47,731,941 | protection against lupus and Graves' disease |
| rs2074190 | 0 | 47,733,844 | |
| rs2240017 | 0 | 47,733,553 | |
| rs4794067 | 2 | 47,731,462 | Aspirin Induced Asthma |
| rs9910408 | 0 | 47,725,508 |
SNPs in the TBX21 gene, also known as T-bet, T-box 21, and T cell-specific T-box transcription factor, have been associated with the function of the immune system's T cells, and in particular, tendencies towards allergies and asthma.
Specific SNPs studied in the TBX21 gene include:
- rs11650354, located downstream of the gene
- rs16947078, located in the fifth intron
- rs2240017, also known as H33Q
- rs4794067, a SNP located in the promoter region
- rs2074190, also known as 390A>G or G130G
- rs9910408, located quite far upstream of the gene
[edit]
| Entrez ID | Interaction Target | Effect on Virus | PubMed ID | Confidence |
|---|---|---|---|---|
| 30009 | HIV-1 Tat | - | 15737643 | + |
