rs16947078
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | 0 | common |
| (A;G) | possible risk for allergic asthma | |
| (G;G) | 8x risk for allergic asthma |
| Reference | GRCh38 38.1/141 |
| Chromosome | 17 |
| Position | 47748134 |
| Gene | TBX21 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs16947078 |
| dbSNP (classic) | rs16947078 |
| ClinGen | rs16947078 |
| ebi | rs16947078 |
| HLI | rs16947078 |
| Exac | rs16947078 |
| Gnomad | rs16947078 |
| Varsome | rs16947078 |
| LitVar | rs16947078 |
| Map | rs16947078 |
| PheGenI | rs16947078 |
| Biobank | rs16947078 |
| 1000 genomes | rs16947078 |
| hgdp | rs16947078 |
| ensembl | rs16947078 |
| geneview | rs16947078 |
| scholar | rs16947078 |
| rs16947078 | |
| pharmgkb | rs16947078 |
| gwascentral | rs16947078 |
| openSNP | rs16947078 |
| 23andMe | rs16947078 |
| SNPshot | rs16947078 |
| SNPdbe | rs16947078 |
| MSV3d | rs16947078 |
| GWAS Ctlg | rs16947078 |
| GMAF | 0.146 |
| Max Magnitude | 0 |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
A large study of Caucasian children has identified this SNP in the TBX21 gene (and one other, rs11650354) as defining a haplotype associated with increased risk for allergic asthma. [PMID 17949803]
The odds ratio associated with rs16947078(G;G) homozygotes compared to rs16947078(A;A) homozygotes for allergic asthma is reported to be 8.13 (CI: 2.5-26.9). Heterozygotes may be at slightly higher risk. [PMID 17949803]
