rs2107301
| Orientation | minus |
| Stabilized | minus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 0 | normal risk |
| (C;T) | ? | |
| (T;T) | 3 | 2.5x higher risk for prostate cancer |
| Reference | GRCh38 38.1/141 |
| Chromosome | 12 |
| Position | 47861787 |
| Gene | VDR |
| is a | snp |
| is | mentioned by |
| dbSNP | rs2107301 |
| dbSNP (classic) | rs2107301 |
| ClinGen | rs2107301 |
| ebi | rs2107301 |
| HLI | rs2107301 |
| Exac | rs2107301 |
| Gnomad | rs2107301 |
| Varsome | rs2107301 |
| LitVar | rs2107301 |
| Map | rs2107301 |
| PheGenI | rs2107301 |
| Biobank | rs2107301 |
| 1000 genomes | rs2107301 |
| hgdp | rs2107301 |
| ensembl | rs2107301 |
| geneview | rs2107301 |
| scholar | rs2107301 |
| rs2107301 | |
| pharmgkb | rs2107301 |
| gwascentral | rs2107301 |
| openSNP | rs2107301 |
| 23andMe | rs2107301 |
| SNPshot | rs2107301 |
| SNPdbe | rs2107301 |
| MSV3d | rs2107301 |
| GWAS Ctlg | rs2107301 |
| GMAF | 0.3572 |
| Max Magnitude | 3 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
rs2107301 is a SNP in the vitamin D VDR receptor gene.
rs2107301(T;T) homozygotes were associated with an ~2.5x higher risk of prostate cancer compared to homozygote carriers of the more common (C) allele in the 630 Caucasian patients studied.[PMID 17932346]
[PMID 19255064
] Vitamin D-related genes, serum vitamin D concentrations and prostate cancer risk.
[PMID 19454612] Vitamin D pathway gene variants and prostate cancer risk.
[PMID 19753122] Analysis of SNPs and haplotypes in vitamin D pathway genes and renal cancer risk.
[PMID 19956101] Overview of the Rapid Response data.
[PMID 21948293] Vitamin D Receptor Gene Variants and Esophageal Adenocarcinoma Risk: A Population-Based Case-Control Study.
[PMID 22576141] No association of vitamin D metabolism-related polymorphisms and melanoma risk as well as melanoma prognosis: a case-control study.
[PMID 24381141] Vitamin D receptor gene polymorphisms and esophageal cancer risk in a Chinese population: a negative study
[PMID 27736940] Vitamin D Receptor Gene Polymorphism and the Risk of Colorectal Cancer: A Nested Case-Control Study.
