rs2107614
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Make rs2107614(C;C) |
| Make rs2107614(C;T) |
| Make rs2107614(T;T) |
| Reference | GRCh38 38.1/142 |
| Chromosome | 12 |
| Position | 793913 |
| Gene | WNK1 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs2107614 |
| dbSNP (classic) | rs2107614 |
| ClinGen | rs2107614 |
| ebi | rs2107614 |
| HLI | rs2107614 |
| Exac | rs2107614 |
| Gnomad | rs2107614 |
| Varsome | rs2107614 |
| LitVar | rs2107614 |
| Map | rs2107614 |
| PheGenI | rs2107614 |
| Biobank | rs2107614 |
| 1000 genomes | rs2107614 |
| hgdp | rs2107614 |
| ensembl | rs2107614 |
| geneview | rs2107614 |
| scholar | rs2107614 |
| rs2107614 | |
| pharmgkb | rs2107614 |
| gwascentral | rs2107614 |
| openSNP | rs2107614 |
| 23andMe | rs2107614 |
| SNPshot | rs2107614 |
| SNPdbe | rs2107614 |
| MSV3d | rs2107614 |
| GWAS Ctlg | rs2107614 |
| Max Magnitude | 0 |
One of 3 SNPs in WNK1 (rs2107614, rs2277869, and rs1159744), reported to help predict blood pressure (BP) response to a thiazide diuretic (hydrochlorothiazide).[PMID 16172412]
This SNP is also cited in US patent 10,465,246 (2019), where one of the claims is prescribing a loop diuretic to a patient as a first line therapy (for high blood pressure), without a beta blocker and without a vasodilator, if the patient carries a rs2107614(C).
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
[PMID 25763762] Potential relationship between single nucleotide polymorphisms used in forensic genetics and diseases or other traits in European population
